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Non-small-cell lung cancer [PDF]

open access: yesNature Reviews Disease Primers, 2015
Lung cancer is one of the most frequently diagnosed cancers and is the leading cause of cancer-related death worldwide. Non-small-cell lung cancer (NSCLC), a heterogeneous class of tumours, represents approximately 85% of all new lung cancer diagnoses. Tobacco smoking remains the main risk factor for developing this disease, but radon exposure and air ...
Gridelli, C   +8 more
  +7 more sources

Non-small cell lung cancer [PDF]

open access: yesBMJ, 2012
This patient describes his experience of multidisciplinary care after his diagnosis of non-small cell lung cancer when he was 15 years ...
Andrew, Hill   +2 more
  +6 more sources

RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets. [PDF]

open access: yes, 2016
RRx-001 is a pan-active, systemically nontoxic epigenetic inhibitor under investigation in advanced non-small cell lung cancer, small-cell lung cancer and high-grade neuroendocrine tumors in a Phase II clinical trial entitled TRIPLE THREAT (NCT02489903),
Brzezniak, Christina   +12 more
core   +10 more sources

Non-small cell lung cancer [PDF]

open access: yesVnitřní lékařství, 2017
Non-small cell lung cancer (NSCLC) represents 80 % of diseases considering all patients with lung cancer. NSCLC comprises all histological types except for the small cell cancer. The treatment is chosen based on a clinical stage, morphological diagnosis and performance status of patients. In the low clinical stages a surgical solution is indicated.
Jana, Skřičková   +2 more
openaire   +2 more sources

Chinese Expert Consensus on Non-small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations (2023 Edition)

open access: yesChinese Journal of Lung Cancer, 2023
With the development of precision diagnosis and treatment for non-small cell lung cancer (NSCLC), the epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations, as a rare subset of EGFR mutaions, have gradually attracted attention ...
Chinese Society of Clinical Oncology (CSCO) Non-small Cell Lung Cancer Committee
doaj   +1 more source

Expert Consensus on Prevention and Treatment of COVID-19 Infection in Patients with Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2023
Corona virus disease 2019 (COVID-19) infection has become a major public health issue affecting human health. The main goal of epidemic prevention and control at the current stage in China is to “protect people’s health and prevent severe cases ...
Non-small Cell Lung Cancer Expert Committee of Chinese Society of Clinical Oncology   +1 more
doaj   +1 more source

LncRNAs in Non-Small-Cell Lung Cancer [PDF]

open access: yesNon-Coding RNA, 2020
Lung cancer is associated with a high mortality, with around 1.8 million deaths worldwide in 2018. Non-small-cell lung cancer (NSCLC) accounts for around 85% of cases and, despite improvement in the management of NSCLC, most patients are diagnosed at advanced stage and the five-year survival remains around 15%.
Lucy Ginn   +3 more
openaire   +4 more sources

Advanced non-small-cell lung cancer: how to manage non-oncogene disease Andrea De Giglio, Alessandro Di Federico, Chiara De

open access: yesDrugs in Context, 2022
The therapeutic approach to patients affected by advanced non-small-cell lung cancer (NSCLC) is facing rapid and continuous evolution. In recent years, the emergence of new treatment strategies, such as immunotherapy and tyrosine kinase inhibitors, has ...
Andrea De Giglio   +5 more
doaj   +1 more source

BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas. [PDF]

open access: yes, 2015
BPTF, a subunit of NURF, is well known to be involved in the development of eukaryotic cell, but little is known about its roles in cancers, especially in non-small-cell lung cancer (NSCLC).
Dai, Meng   +14 more
core   +8 more sources

Overexpression of the non-coding SOX2OT variants 4 and 7 in lung tumors suggests an oncogenic role in lung cancer [PDF]

open access: yes, 2016
Despite the advances in cancer therapy, lung cancer still remains the most leading cause of cancer death worldwide. The long non-coding RNAs (lncRNAs) are recently introduced as novel regulators of human cancers. SOX2 overlapping transcript (SOX2OT) is a
Ghanei, M.   +4 more
core   +1 more source

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