Sex matters in CSU: Women face greater burden and poorer urticaria control, especially in midlife-CURE insights. [PDF]
Chronic spontaneous urticaria affects more females than males, with predominance starting at age 31. The rates of several symptoms, including angioedema, sleep disturbance and systemic symptoms, are significantly higher in females than in males. Overall, females face greater burden and poorer urticaria control.
Kocatürk E +40 more
europepmc +2 more sources
International survey of treatment practices for atopic dermatitis in pregnant and breastfeeding women: Physician perspectives. [PDF]
Summary Background and Objectives Systemic treatment of pregnant/breastfeeding atopic dermatitis (AD) patients is challenging due to limited safety data. We explored treatment practices with systemic agents, including the guideline‐recommended cyclosporine as the first systemic choice as well as emerging therapies, in this vulnerable population ...
Pereira MP +34 more
europepmc +2 more sources
Optimizing Alternating Current Electrical Stimulation Parameters to Enhance Osteoblasts Differentiation. [PDF]
Alternating current stimulation at 10 Hz and 500–750 mV/mm optimizes osteoblastic differentiation, viability, and morphological maturation. This study establishes critical parameters for utilizing electrical signaling in bone tissue engineering, offering a promising strategy to accelerate bone regeneration and early‐stage cell development.
Bocio-Núñez J +8 more
europepmc +2 more sources
Exploring the impact of chronic urticaria profile as a key predictor of alexithymia: A cross-sectional study. [PDF]
Abstract Introduction The relationship between chronic urticaria (CU) and alexithymia, a cognitive‐affective impairment characterized by difficulty in identifying and expressing emotions, is complex and underexplored. This study aimed to identify predictors of alexithymia in CU patients by focusing on the impact of coexisting mental illnesses and ...
Ojeda IC +29 more
europepmc +2 more sources
Cost-of-illness analysis of chronic urticaria clinical management in five countries of Latin America. [PDF]
Abstract Introduction Chronic spontaneous urticaria (CSU) is a disease with a high impact on the quality of life of patients. There are some evaluations of the economic cost of the disease in developed countries, but there is little information about the economic cost of the disease in developing countries. Our aim was to assess the economic diagnostic
Sánchez J +8 more
europepmc +2 more sources
A concept for integrated care pathways for atopic dermatitis—A GA2LEN ADCARE initiative
Abstract Introduction The integrated care pathways for atopic dermatitis (AD‐ICPs) aim to bridge the gap between existing AD treatment evidence‐based guidelines and expert opinion based on daily practice by offering a structured multidisciplinary plan for patient management of AD.
Torsten Zuberbier +107 more
wiley +1 more source
This article covers the career pathway of a research‐trained scientist to an immunology educator in a university setting.
Maurizio Costabile
wiley +1 more source
Our results supported a preliminary improvement in clinical scores (VAS, RCAT, TNSS), and a significant improvement in quality of life (PRQLQ) scores above minimal important differences. These findings show the need of conducting future trials to evaluate the efficacy of synbiotics in children with AR.
Cesar A. Galvan Calle +4 more
wiley +1 more source
How reliably can algorithms identify eosinophilic asthma phenotypes using non‐invasive biomarkers?
Abstract Background and Aims Asthma is a heterogeneous respiratory disease that encompasses different inflammatory and functional endophenotypes. Many non‐invasive biomarkers has been investigated to its pathobiology. Heany et al proposed a clinical algorithm that classifies severe asthmatic patients into likely‐eosinophilic phenotypes, based on ...
Diana Betancor +22 more
wiley +1 more source
Risk factors for systemic reactions in typical cold urticaria: Results from the COLD‐CE study
The COLD‐CE study was carried out at 32 UCAREs from 19 countries and four continents. Among 551 ColdU patients, 75% had positive local CST (i.e., typical ColdU) and ColdA occurred in 37% of the latter. For the first time, we propose the criteria for adrenaline autoinjector prescription for patients with typical ColdU.Abbreviations: ColdA, cold‐induced ...
Mojca Bizjak +46 more
wiley +1 more source

