Nuclear proteome analysis suggests spatial and temporal compartmentalization of metabolic enzymes during Trypanosoma cruzi cell cycle. [PDF]
Menezes AP +6 more
europepmc +1 more source
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang +12 more
wiley +1 more source
Direct detection and quantification of HIV particles and their envelope trimers bound by combinations of broadly neutralizing antibodies. [PDF]
Dasgupta S +5 more
europepmc +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Accessible STORM Imaging: An Optimized Workflow for Conventional Widefield Epifluorescence/TIRF Setups. [PDF]
Fernández de Córdoba J +2 more
europepmc +1 more source
Nx3 Is a Z-Disk Structural and Signaling Hub That Is Reduced in Heart Failure. [PDF]
Linke WA +31 more
europepmc +1 more source
Cognitive Reablement Using Digital Voice Assistants for People Living With Dementia or Mild Cognitive Impairment: A Co-Design Study. [PDF]
Yiannis T +7 more
europepmc +1 more source
Unraveling Nanoplastics-Enzyme Interactions: Physicochemical, Structural, Functional, and Cell Biological Characterization of α-Amylase-Nanoplastics Complexes. [PDF]
Sieg H +6 more
europepmc +1 more source

