Results 71 to 80 of about 306,111 (180)

Dual Disease Burden: Growing Older with Congenital Heart Disease and Hereditary Metabolic and Connective Tissue Disorders—Data from the PATHFINDER-CHD Registry on Heart Failure

Geriatrics
Background: Advances in diagnosis and treatment have led to a growing population of adults with congenital heart disease (ACHD). Despite increasing life expectancy, their clinical needs—especially in older age—remain poorly defined.
Ann-Sophie Kaemmerer-Suleiman, Frank Harig, Annika Freiberger, Oliver Dewald, Stephan Achenbach, Aysenur Akyol, Helena Dreher, Anna Engel, Peter Ewert, Sebastian Freilinger, Jürgen Hörer, Christopher Hohmann, Stefan Holdenrieder, Robert David Pittrow, Harald Kaemmerer, Renate Kaulitz, Frank Klawonn, Christian Meierhofer, Steffen Montenbruck, Nicole Nagdyman, Rhoia Neidenbach, Elsa Ury, Leonard Bernhard Pittrow, Benjamin Alexander Pittrow, Fabian von Scheidt, Nicole Wolfrum, Michael Huntgeburth, Pelagija Zlatic, Mathieu N. Suleiman, Fritz Mellert   +29 more
doaj   +1 more source

Effects of Withaferin A on Mouse Models of Alexander Disease

, 2015
Alexander disease is a rare neurodegenerative disorder which is caused by the accumulation of glial fibrillary acidic protein (GF AP) resulting in aggregates termed Rosenthal Fibers (RFs) in the central nervous system.
Lewis, Diana
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Alexander Disease

The Journal of Pediatrics, 2013
Dimitrios I, Zafeiriou, Pinelopi, Dragoumi, Euthymia, Vargiami   +2 more
openaire   +4 more sources

Chronic inflammation degrades CD4 T cell immunity to prior vaccines in treated HIV infection

Nature Communications
To date, our understanding of how HIV infection impacts vaccine-induced cellular immunity is limited. Here, we investigate inflammation, immune activation and antigen-specific T cell responses in HIV-uninfected and antiretroviral-treated HIV-infected ...
Melissa Kießling, John J. Cole, Sabrina Kübel, Paulina Klein, Klaus Korn, Amy R. Henry, Farida Laboune, Slim Fourati, Ellen Harrer, Thomas Harrer, Daniel C. Douek, Klaus Überla, Krystelle Nganou-Makamdop   +12 more
doaj   +1 more source

Magnetic resonance spectroscopy in the diagnostic evaluation of brainstem lesions in alexander disease.

, 2011
Alexander disease is a progressive neurodegenerative disease, which can present with brainstem lesions with imaging characteristics similar to multifocal low-grade glioma, thus presenting a diagnostic dilemma.
Macpherson, LK, English, Martin, James E. Davison, Philip, S, Martin W. English, Nigel P. Davies, Sunny Philip, Davies, Nigel, Gissen, Paul, Andrew C. Peet, Peet, Andrew, Davison, James, Lesley K. R. MacPherson, Paul Gissen   +13 more
core   +1 more source

Fontan associated protein-losing enteropathy is linked to distinct metabolic and hepatic alterations

Scientific Reports
The univentricular Fontan circulation is associated with long-term multiorgan complications, including protein-losing enteropathy (PLE). While hemodynamic and lymphatic contributors to PLE have been described, its systemic metabolic signature remains ...
Christian Schroeder, Fabian B. Fahlbusch, Robert Cesnjevar, Manfred Rauh, Sven Dittrich, Julia Moosmann   +5 more
doaj   +1 more source

Preventing Chronic Disease (PCD) [PDF]

Publication date from document properties.GIS_collection.pdfChronic Disease Mapping, an Important Strategy and Tool for Health Promotion / Hacker K, Kaufmann R. Chronic Disease Mapping, an Important Strategy and Tool for Health Promotion.

core  

PATHFINDER-CHD: prospective registry on adults with congenital heart disease, abnormal ventricular function, and/or heart failure as a foundation for establishing rehabilitative, prehabilitative, preventive, and health-promoting measures: rationale, aims, design and methods

BMC Cardiovascular Disorders
Background Adults with congenital heart defects (ACHD) globally constitute a notably medically underserved patient population. Despite therapeutic advancements, these individuals often confront substantial physical and psychosocial residua or sequelae ...
Sebastian Freilinger, Harald Kaemmerer, Robert D. Pittrow, Stefan Achenbach, Stefan Baldus, Oliver Dewald, Peter Ewert, Annika Freiberger, Matthias Gorenflo, Frank Harig, Christopher Hohmann, Stefan Holdenrieder, Jürgen Hörer, Michael Huntgeburth, Michael Hübler, Niko Kohls, Frank Klawonn, Rainer Kozlik-Feldmann, Renate Kaulitz, Dirk Loßnitzer, Friedrich Mellert, Nicole Nagdyman, Johannes Nordmeyer, Benjamin A. Pittrow, Leonard B. Pittrow, Carsten Rickers, Stefan Rosenkranz, Jörg Schelling, Christoph Sinning, Mathieu N. Suleiman, Yskert von Kodolitsch, Fabian von Scheidt, Ann-Sophie Kaemmerer-Suleiman   +32 more
doaj   +1 more source

Drone-based geospatial prediction modeling identifies Fasciola hepatica infection risk in the Cusco Highlands of Peru

Infectious Diseases of Poverty
Background Fascioliasis is a neglected infectious disease affecting agricultural communities worldwide, with the Peruvian Andes among the most severely affected regions.
Bryan Fernandez-Camacho, Antony Barja, Luis C. Revilla, Rodrigo A. Ore, Jose L. Alccacontor-Muñoz, Maria L. Morales, Melinda B. Tanabe, Gabriel Carrasco-Escobar, Miguel M. Cabada, Fasciola Tropical Medicine Research Center - Peru   +9 more
doaj   +1 more source

Diagnosis by whole exome sequencing of atypical infantile onset Alexander disease masquerading as a mitochondrial disorder

, 2014
Introduction: There are many similarities, both clinical and radiological, between mitochondrial leukoencephalopathies and Alexander disease, an astrogliopathy.
Blumkin, Lubov, Nishri, Daniella, Lerman-Sagie, Tally, Leshinsky-Silver, Esther, Lev, Dorit, Henneke, Marco, Ben-Sira, Liat, Edvardson, Simon   +7 more
core   +1 more source