Results 1 to 10 of about 91,538 (160)

Autoimmune glial fibrillary acidic protein astrocytopathy [PDF]

Current Opinion in Neurology, 2019
Purpose of review To describe a recently characterized autoimmune, inflammatory central nervous system (CNS) disorder known as autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy. Recent findings Affected patients present with symptoms of one or more of meningitis ...
Kunchok, Amy, Zekeridou, Anastasia, McKeon, Andrew   +2 more
openaire   +4 more sources

Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases [PDF]

, 2013
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Brunkhorst, Robert, Förch, Christian, Mayer, Christoph, Niessner, Marion, Pfeilschifter, Waltraud, Steinmetz, Helmuth   +5 more
core   +2 more sources

Demonstration of astrocytes in cultured amniotic fluid cells of three cases with neural-tube defect [PDF]

, 1981
We have investigated the origin of rapidly adhering (RA) cells in three cases of neural tube defects (two anencephali, one encephalocele). We were able to demonstrate the presence of glial fibrillary acidic (GFA) protein in variable percentages (4–80 ...
AD Smith, AK Buamah, B Nørgaard-Pedersen, CB Laurell, CM Gosden, CM Gosden, CM Gosden, D Bignami, E Crouch, GR Sutherland, LB Chen, LF Eng, LF Eng, M Schachner, M Schachner, M Seppälä, NJ Wald, S Sarkar, T Voigtländer   +18 more
core   +1 more source

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium [PDF]

, 2020
Importance: There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC). Objective: To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.
Broglio, Steven P., Brooks, M. Alison, Cameron, Kenneth L., Campbell, Darren E., CARE Consortium Investigators, DiFiori, Jon, Duma, Stephan, Foroud, Tatiana, Gill, Jessica, Giza, Christopher C., Goldman, Joshua, Guskiewicz, Kevin, Harezlak, Jaroslaw, Houston, Megan N., Huber, Daniel L., Jackson, Jonathan C., Katz, Barry P., McAllister, Thomas W., McCrea, Michael, McGinty, Gerald, Meier, Timothy B., Mihalik, Jason, Nelson, Lindsay D., Pasquina, Paul, Rowson, Steven, Saykin, Andrew J., Svoboda, Steven J.   +26 more
core   +1 more source

Protein kinase a distribution differentiates human glioblastoma from brain tissue [PDF]

, 2017
Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to ...
Caretta, Antonio, D\u2019Avella, Domenico, Denaro, Luca, Mucignat-Caretta, Carla   +3 more
core   +2 more sources

Glial Fibrillary Acidic Protein Autoimmunity

Neurology, 2022
To report the clinical, biological, and imaging features and clinical course of a French cohort of patients with glial fibrillary acidic protein (GFAP) autoantibodies.We retrospectively included all patients who tested positive for GFAP antibodies in the CSF by immunohistochemistry and confirmed by cell-based assay using cells expressing human GFAPα ...
Gravier-Dumonceau, Alice, Ameli, Roxana, Rogemond, Veronique, Ruiz, Anne, Joubert, Bastien, Muniz-Castrillo, Sergio, Vogrig, Alberto, Picard, Geraldine, Ambati, Aditya, Benaiteau, Marie, Rulquin, Florence, Ciron, Jonathan, Deiva, Kumaran, Broucker, Thomas, Kremer, Laurent, Kerschen, Philippe, Sellal, François, Bouldoires, Bastien, Genet, Roxana, Biberon, Julien, Bigot, Adrien, Duval, Fanny, Issa, Nahema, Rusu, Elena-Camelia, Goudot, Mathilde, Dutray, Anais, Devoize, Jean Louis, Hopes, Lucie, Kaminsky, Anne-Laure, Philbert, Marion, Chanson, Eve, Leblanc, Amelie, Morvan, Erwan, Andriuta, Daniela, Diraison, Philippe, Mirebeau, Gabriel, Derollez, Celine, Bourg, Veronique, Bodard, Quentin, Fort, Clementine, Grigorashvili-Coin, Irina, Rieul, Guillaume, Molinier-Tiganas, Daniela, Bonnan, Mickael, Tchoumi, Thierry, Honnorat, Jerome, Marignier, Romain   +46 more
openaire   +4 more sources

The effects of pioglitazone, a PPARγ receptor agonist, on the abuse liability of oxycodone among nondependent opioid users [PDF]

, 2016
Aims: Activation of PPARγ by pioglitazone (PIO) has shown some efficacy in attenuating addictive-like responses in laboratory animals. The ability of PIO to alter the effects of opioids in humans has not been characterized in a controlled laboratory ...
Alonzo, Banks, Begelow, Beitner-Johnson, Berger, Bhargava, Bland, Bush, Bussiere, Carr, Chang, Cone, Cooper, de Guglielmo, de Guglielmo, Dhalla, Eisenstein, Eisenstein, Eisenstein, Eng, Ferguson, Fraser, Gagnon, Garrido, Gelinas, Gillies, Hopkins, Hutchinson, Hutchinson, Hutchinson, Jeanne M. Manubay, Jermaine D. Jones, Johnston, Katz, Kielian, Kreutzberg, Ledeboer, Levine, Maria A. Sullivan, Marie-Claire, Martin, Mellon, Moreno, Nakajima, Narita, Pacifici, Pelvig, Roberto Ciccocioppo, Sandra D. Comer, Sarruf, Shanthi Mogali, Song, SPSS, Stoll, Stopponi, Stopponi, Strain, Sweitzer, Tawfik, Tontonoz, Verena E. Metz, Verkhratsky, Walker, Walker, Walsh, Walsh, Watkins, Watkins, Wightman, Woods, Wybran, Zacny, Zacny, Zacny, Zhang   +74 more
core   +1 more source

Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]

, 2014
BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A, Loo, Rachel R Ogorzalek, Shen, Sean, Wanner, Ina-Beate   +3 more
core   +1 more source

Radial glia in the proliferative ventricular zone of the embryonic and adult turtle, Trachemys scripta elegans. [PDF]

, 2014
To better understand the role of radial glial (RG) cells in the evolution of the mammalian cerebral cortex, we investigated the role of RG cells in the dorsal cortex and dorsal ventricular ridge of the turtle, Trachemys scripta elegans.
Clinton, Brian K, Cunningham, Christopher L, Kriegstein, Arnold R, Martínez-Cerdeño, Verónica, Noctor, Stephen C   +4 more
core   +1 more source

The determination of glial fibrillary acidic protein for the diagnosis and histogenetic study of central nervous system tumors: a study of 152 cases. [PDF]

, 1985
Glial fibrillary acidic protein (GFAP) was purified from human spinal cord and cerebral white matter. GFAP was localized by an immuno-peroxidase method in normal adult and fetal human brains, rat brains, and 152 central nervous system (CNS) tumors.
Doi, Kenji, Hamaya, Kazuo, Nishimoto, Akira, Tanaka, Toshio   +3 more
core   +1 more source