Results 1 to 10 of about 70,938 (290)

GLIAL FIBRILLARY ACIDIC PROTEIN IN HUMAN GLIOMAS

Neuropathology and Applied Neurobiology, 1978
The presence of GFA protein, an astrocyte specific antigen, was investigated in surgical biopsies of ninety‐five gliomas using an immunoperoxidase detection method. In some cases electron microscopy was added and also in one tumour immunoelectron microscopy. The results were correlated with the histological classification and grading of the tumours. In
VANDERMEULEN, JDM, HOUTHOFF, HJ, EBELS, EJ   +2 more
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Phosphorylation of the glial fibrillary acidic protein

Journal of Neuroscience Research, 1990
AbstractThe glial fibrillary acidic protein (GFAP) was found to be phosphorylated in vivo after intracerebral injection of [32P]‐orthophosphate, in brain Slices, and in a cell free system. The phosphorylated proteins were separated by two‐dimensional gel electrophoresis and then transferred to nitrocellulose sheets.
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Glial Fibrillary Acidic Protein in Brain Tumors

Oncology, 2009
Glial fibrillary acidic protein has been widely used in neurobiology and neuropathology as a specific marker for normal and abnormal astrocytes. Here, we report the immunostaining of 107 brain tumors and controls using an antiserum against glial fibrillary acidic protein. Selection of astroglia-derived tumors was easy and of high accuracy.
E, Luevano, M, Tena, A, Zamora, J, Sotelo   +3 more
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Glial Fibrillary Acidic Protein in Tuberous Sclerosis

Psychiatry and Clinical Neurosciences, 1983
Abstract: We examined two cases of tuberous sclerosis for the presence of glial fibrillary acidic protein (GFAP) using the immunoperoxidase technique. The majority of abnormal giant cells in the cerebral cortex showed no reaction to anti‐GFAP. Some abnormal cells in the cortical tuber and white matter showed a weak positive reaction.
M, Tobo, Y, Mitsuyama, T, Kaku
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Glial fibrillary acidic protein and cartilage

Acta Neuropathologica, 1989
The presence of glial fibrillary acidic protein was tested for in cartilage of bronchi, trachea, pulmonary hamartomas, articular cartilage and chondrosarcomas. The cytoplasm of most chondrocytes in bronchi stained strongly positive, whilst in hamartomas only small foci at the edges reacted. Staining in the trachea was weak.
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Glial Fibrillary Acidic Protein in the Diagnosis and Prognosis of Malignant Glial Tumors

Bulletin of Experimental Biology and Medicine, 2020
Serum levels of glial fibrillar acidic protein (GFAP) were analyzed in 317 patients with primary and metastatic tumors of the brain, 78 patients with neurological diseases, and 66 normal subjects. A significant increase in the basal level of GFAP was typical of patients with glioblastomas in comparison with other groups (patients with astrocytomas ...
N V, Lyubimova, Yu S, Timofeev, A A, Mitrofanov, A Kh, Bekyashev, Z A, Goncharova, N E, Kushlinskii   +5 more
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Glial Fibrillary Acidic Protein in Astrocytes in the Human Neocortex

Neuroscience and Behavioral Physiology, 2005
Glial fibrillary acidic protein (GFAP) is a brain astrocyte-expressed protein that is recognized as one of the main immunohistochemical markers of these cells. The aim of the present study was to investigate the structure of GFAP-positive astrocytes of human neocortex.
D E, Korzhevskii, V A, Otellin, I P, Grigor'ev   +2 more
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Glial fibrillary acidic protein (GFAP)

Journal of the Neurological Sciences, 1979
Abstract The extraction and purification of glial fibrillary acidic protein (GFAP) from human fibrillary cerebellar astrocytoma is described. Using an immunoperoxidase method, antisera raised to the protein showed specific staining of astrocytes in normal spinal cord and in tumours of astrocytic origin.
J.W. Palfreyman, D.G.T. Thomas, J.G. Ratcliffe, D.I. Graham   +3 more
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Suppression of Glial Tumor Growth by Expression of Glial Fibrillary Acidic Protein

Neurochemical Research, 1999
We examined the effect of expression of glial fibrillary acidic protein (GFAP) on the tumor growth of astrocytoma in vivo. When rat astrocytoma C6 cells were injected subcutaneously in athymic mice, the cells produced tumors that grew rapidly. The tumor growth of C6 cells transfected with GFAP cDNA was significantly reduced compared to that of control ...
M, Toda, M, Miura, H, Asou, I, Sugiyama, T, Kawase, K, Uyemura   +5 more
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Glial Fibrillary Acid Protein in Medulloblastomas

1983
Glial Fibrillary Acid Protein (GFAP) is regarded as an astroglial-specific component and its presence can therefore be used to control the degree of differentiation of glial elements (BIGNAMI and DAHL, 1974; 1977). This method is being used with increasing frequency in neuro-oncology, with some contradictory results, however (for review see De ARMOND ...
E. Schindler, F. Gullotta
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