Results 31 to 40 of about 3,631,478 (254)

Case report: Excessive daytime sleepiness as a presenting manifestation of autoimmune glial fibrillary acidic protein astrocytopathy

Frontiers in Immunology, 2023
Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a recently discovered autoimmune inflammatory disease of the central nervous system.
Mingyang Tang, Shuo Huang, Weitong Guo, Junfang Zhou, Zhencan Huang, Wanru Li, Qingqing Sun, Zan Wang   +7 more
doaj   +1 more source

Changes in Plasma Glial Fibrillary Acidic Protein in Children Receiving Sevoflurane Anesthesia: A Preliminary Randomized Trial

, 2021
We investigated changes in plasma glial fibrillary acidic protein concentration during sevoflurane anesthesia induction in children < 3 years old and determined the effect of co-administering dexmedetomidine. This preliminary randomized trial included
Jin-Tae Kim, Eun-Hee Kim, Hee-Soo Kim, Hyunyee Yoon, Sung-Ae Cho, Sang-Hwan Ji, Ji-Hyun Lee, Young-Eun Jang   +7 more
core   +1 more source

Genetic background affects human glial fibrillary acidic protein promoter activity. [PDF]

PLoS ONE, 2013
The human glial fibrillary acidic protein (hGFAP) promoter has been used to generate numerous transgenic mouse lines, which has facilitated the analysis of astrocyte function in health and disease.
Xianshu Bai, Aiman S Saab, Wenhui Huang, Isolde K Hoberg, Frank Kirchhoff, Anja Scheller   +5 more
doaj   +1 more source

Abnormal evoked potentials in autoimmune glial fibrillary acidic protein astrocytopathy

eNeurologicalSci, 2020
Autoimmune GFAP astrocytopathy is a new clinical entity and only a limited number of cases have been reported. Here we report the results of multimodal central conduction studies performed in a case of this disorder.A 72-year-old woman developed gradual ...
Ryo Tokimura, Nozomu Matsuda, Shunsuke Kobayashi, Akio Kimura, Kazuaki Kanai   +4 more
doaj   +1 more source

A Rare Case of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

, 2022
• Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a rare autoimmune inflammatory disorder typically manifesting as a meningoencephalomyelitis first identified in 20161 .
Fellows, Jonathan, Doty, Jonathan
core   +1 more source

A Case of Adult-Onset Alexander Disease Featuring Severe Atrophy of the Medulla Oblongata and Upper Cervical Cord on Magnetic Resonance Imaging

Case Reports in Neurology, 2012
Adult-onset Alexander disease (AOAD) has been increasingly recognized since the identification of the glial fibrillary acidic protein gene mutation in 2001.
Tadahiro Yonezu, Shoichi Ito, Kazuaki Kanai, Saeko Masuda, Kazumoto Shibuya, Satoshi Kuwabara   +5 more
doaj   +1 more source

Evaluation of Blood Glial Fibrillary Acidic Protein as a Potential Marker in Huntington's Disease [PDF]

, 2021
Objective: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder. Neurofilament light protein (NfL) is correlated with clinical severity of HD but relative data are the lack in the Chinese population.
Lishan Lin, Gang Du, Zhong Pei, Chen, Dingbang, Tengteng Wu, Huang, Yue, Huajing You, Yue Huang, Wu, Tengteng, Chao Wu, Xunhua Li, Dingbang Chen, You, Huajing, Jean-marc Burgunder, Lin, Lishan, Zeng, Yixuan, Wu, Chao, Burgunder, Jean-Marc, Pei, Zhong, Yixuan Zeng, Du, Gang, Li, Xunhua   +21 more
core   +2 more sources

Expression of myelin basic protein and glial fibrillary acidic protein genes in human glial tumors [PDF]

, 2009
Проведенo аналіз експресії генів основного білка мієліну (MBP, myelin basic protein) та гліального фібрилярного кислого білка (GFAP, glial fibrillary acydic protein) в гліальних пухлинах головного мозку людини для визначення специфічності експресії цих ...
Шостак, К.О., Розуменко, В.Д., Зозуля, Ю.П., Білецький, А.В, Кавсан, В.М., Малишева, Т.А., Шамаєв, М.І., Бойко, О.І., Ключка, В.М., Дмитренко, В.В.   +9 more
core   +2 more sources

Changes in the levels of serum glial fibrillary acidic protein and the correlation with outcomes in severe traumatic brain injury patients

SAGE Open Medicine
Purpose: Glial fibrillary acidic protein serves as a biomarker indicative of astroglial injury, particularly following instances of severe traumatic brain injury.
Kien Trung Nguyen, Tuan Dinh Le, Manh Dang Le, Tien Viet Tran, Cong Van Pham, Ba Van Dang, Son Tien Nguyen, Tam Chi Nguyen, Huy Quang Nguyen, Anh The Vu, Thuc Luong Cong, Hoang Duong Huy, Hai Anh Vu   +12 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source