Results 1 to 10 of about 158,057 (161)

Alexander disease GFAP R239C mutant shows increased susceptibility to lipoxidation and elicits mitochondrial dysfunction and oxidative stress

open access: yesRedox Biology, 2022
Alexander disease is a fatal neurological disorder caused by mutations in the intermediate filament protein Glial Fibrillary Acidic Protein (GFAP), which is key for astrocyte homeostasis.
Alvaro Viedma-Poyatos   +2 more
exaly   +3 more sources

Astrocytic reaction in furious and paralytic forms of rabies with reference to GFAP expression in dog brain samples positive for rabies [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2022
The aim of this study was to evaluate the astrocytic reaction in infected brains of dogs in that had been afflicted with the furious and paralytic form of rabies.
A. Shruthi   +3 more
doaj   +1 more source

Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Intracerebral hemorrhage (ICH) occurs mostly in the striatum. In ICH, blood prolactin level increases 3-fold. The effects of intracerebroventricular injection (ICV) of prolactin on motor disorders will be investigated. Materials and Methods:
Shiba Yousefvand   +6 more
doaj   +1 more source

Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells [PDF]

open access: yesBioImpacts, 2022
Introduction: Neurodegenerative diseases are accompanied by loss of neuronal function and integrity. Stem cell therapy is utilized to regenerate neurons to repair the damaged area.
Aisha Ishaque   +5 more
doaj   +1 more source

Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases [PDF]

open access: yes, 2013
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Brunkhorst, Robert   +5 more
core   +13 more sources

Effect of involuntary and voluntary exercise in an enrichment environment on astrogliosis reaction of hippocampus white matter in type 3 diabetic rat models [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2022
Background and Purpose: Alzheimer's disease (AD) is associated with decreases in neurons in several important areas for memory and learning in the brain, especially in the hippocampus. AD is a progressive brain disorder that causes gradual loss of memory,
Masoud Jamshidi   +2 more
doaj   +1 more source

A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features

open access: yesIndian Journal of Pathology and Microbiology, 2021
Pilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis.
Siddhi Gaurish Sinai Khandeparkar   +3 more
doaj   +1 more source

Relapsing Autoimmune GFAP Astrocytopathy: Case Report [PDF]

open access: yesАнналы клинической и экспериментальной неврологии, 2023
Introduction. Glial fibrillary acidic protein (GFAP) is the main component of intermediate astrocyte filaments. In 2016, anti-GFAP antibodies (Ab) were identified as the specific biomarker for the first established CNS inflammatory disorder subsequently ...
Ekaterina O. Chekanova   +7 more
doaj   +1 more source

Immunohistochemical analysis of GFAP expression in the experimental sepsis-associated encephalopathy

open access: yesPatologìâ, 2021
Pathophysiology of sepsis-associated encephalopathy (SAE) is linked to blood-brain barrier breakdown, neuroinflammation and neurotransmitter imbalance in the brain. Astroglia, the most abundant cell population within the brain, plays the critical role in
T. V. Shulyatnikova, V. O. Tumaskyi
doaj   +1 more source

The effect of addition protein, phosphatidylcholine, phosphatidylserine, and inulin on GFAP levels of acute ischemic stroke patients at Dr. Kariadi Hospital, Semarang

open access: yesJurnal Gizi Indonesia: The Indonesian Journal of Nutrition, 2021
Background: The occurrence of ischemia causes a loss of energy to switch to anaerobic processes resulting in acidosis due to reduced Adenosina Triphosphate (ATP). This condition makes neuron cells apoptotic. Apoptotic of several biochemical substrates in
Diah Retno Wahyuningrum   +2 more
doaj   +1 more source

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