ASN Neuro, 2021 Expression of the GFAP gene has attracted considerable attention because its onset is a marker for astrocyte development, its upregulation is a marker for reactive gliosis, and its predominance in astrocytes provides a tool for their genetic manipulation.
Michael Brenner, Albee Messing
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ASN Neuro, 2020 Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse as structural biology, cell biology, gene expression, basic neuroscience, clinical genetics and gene ...
Albee Messing, Michael Brenner
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Alexander-disease mutation ofGFAPcauses filament disorganization and decreased solubility of GFAP [PDF]
Journal of Cell Science, 2005 Alexander disease is a fatal neurological illness characterized by white-matter degeneration and the formation of astrocytic cytoplasmic inclusions called Rosenthal fibers, which contain the intermediate filament glial fibrillary acidic protein (GFAP), the small heat-shock proteins HSP27 and αB-crystallin, and ubiquitin. Many Alexander-disease patients
Victoria C, Hsiao +6 more
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The
Journal of NeurochemistryAbstract Glial fibrillary acidic protein (GFAP) is a well‐established biomarker of reactive astrogliosis in the central nervous system because of its elevated levels following brain injury and various neurological disorders.
Dea Gogishvili +6 more
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Astrocytic reaction in furious and paralytic forms of rabies with reference to GFAP expression in dog brain samples positive for rabies [PDF]
Journal of Veterinary and Animal Sciences, 2022 The aim of this study was to evaluate the astrocytic reaction in infected brains of dogs in that had been afflicted with the furious and paralytic form of rabies.
A. Shruthi +3 more
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Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Intracerebral hemorrhage (ICH) occurs mostly in the striatum. In ICH, blood prolactin level increases 3-fold. The effects of intracerebroventricular injection (ICV) of prolactin on motor disorders will be investigated. Materials and Methods:
Shiba Yousefvand +6 more
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Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells [PDF]
BioImpacts, 2022 Introduction: Neurodegenerative diseases are accompanied by loss of neuronal function and integrity. Stem cell therapy is utilized to regenerate neurons to repair the damaged area.
Aisha Ishaque +5 more
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Effect of involuntary and voluntary exercise in an enrichment environment on astrogliosis reaction of hippocampus white matter in type 3 diabetic rat models [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2022 Background and Purpose: Alzheimer's disease (AD) is associated with decreases in neurons in several important areas for memory and learning in the brain, especially in the hippocampus. AD is a progressive brain disorder that causes gradual loss of memory,
Masoud Jamshidi +2 more
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Indian Journal of Pathology and Microbiology, 2021 Pilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis.
Siddhi Gaurish Sinai Khandeparkar +3 more
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Relapsing Autoimmune GFAP Astrocytopathy: Case Report [PDF]
Анналы клинической и экспериментальной неврологии, 2023 Introduction. Glial fibrillary acidic protein (GFAP) is the main component of intermediate astrocyte filaments. In 2016, anti-GFAP antibodies (Ab) were identified as the specific biomarker for the first established CNS inflammatory disorder subsequently ...
Ekaterina O. Chekanova +7 more
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