Results 1 to 10 of about 137,539 (311)
Response of Astrocyte Subpopulations Following Spinal Cord Injury
Cells, 2022 There is growing appreciation for astrocyte heterogeneity both across and within central nervous system (CNS) regions, as well as between intact and diseased states. Recent work identified multiple astrocyte subpopulations in mature brain. Interestingly,
R. Vivian Allahyari +9 more
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Molecular Neurodegeneration, 2023 Background Previous studies show that antibiotic-mediated (abx) alteration of the gut microbiome (GMB) results in a reduction of amyloid beta (Aβ) plaques and proinflammatory microglial phenotype in male APPPS1-21 mice.
Sidhanth Chandra +9 more
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Cells, 2022 Astrocytes have many important functions in the brain, but their roles in psychiatric disorders and their responses to psychotropic medications are still being elucidated.
Xiaolu Zhang +10 more
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Adenosine-independent regulation of the sleep–wake cycle by astrocyte activity
Cell Discovery, 2023 Astrocytes play a crucial role in regulating sleep–wake behavior, and adenosine signaling is generally thought to be involved. Here we show multiple lines of evidence supporting that modulation of the sleep–wake behavior by astrocyte Ca2+ activity could ...
Wanling Peng +10 more
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Dynamic Transitions in Neuronal Network Firing Sustained by Abnormal Astrocyte Feedback
Neural Plasticity, 2020 Astrocytes play a crucial role in neuronal firing activity. Their abnormal state may lead to the pathological transition of neuronal firing patterns and even induce seizures.
Yangyang Yu +4 more
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Molecular Brain, 2021 The morphological dynamics of astrocytes are altered in the hippocampus during memory induction. Astrocyte–neuron interactions on synapses are called tripartite synapses. These control the synaptic function in the central nervous system.
Moonseok Choi +5 more
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Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes
Cells, 2019 Vimentin (VIM) is an intermediate filament (nanofilament) protein expressed in multiple cell types, including astrocytes. Mice with VIM mutations of serine sites phosphorylated during mitosis (VIMSA/SA) show cytokinetic failure in fibroblasts and lens ...
Yolanda de Pablo +6 more
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Glutamate mediated astrocytic filtering of neuronal activity. [PDF]
PLoS Computational Biology, 2014 Neuron-astrocyte communication is an important regulatory mechanism in various brain functions but its complexity and role are yet to be fully understood.
Gilad Wallach +6 more
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Scientific Reports, 2022 An emerging link between circadian clock function and neurodegeneration has indicated a critical role for the molecular clock in brain health. We previously reported that deletion of the core circadian clock gene Bmal1 abrogates clock function and ...
Celia A. McKee +5 more
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Parkinson's Disease, 2012 Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes.
Simone A. van den Berge +3 more
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