Results 21 to 30 of about 124,424 (305)
Astrocytes in schizophrenia [PDF]
Brain and Neuroscience Advances, 2021 Schizophrenia is a severe and clinically heterogenous mental disorder affecting approximately 1% of the population worldwide. Despite tremendous achievements in the field of schizophrenia research, its precise aetiology remains elusive. Besides dysfunctional neuronal signalling, the pathophysiology of schizophrenia appears to involve molecular and ...
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Dynamic Transitions in Neuronal Network Firing Sustained by Abnormal Astrocyte Feedback
Neural Plasticity, 2020 Astrocytes play a crucial role in neuronal firing activity. Their abnormal state may lead to the pathological transition of neuronal firing patterns and even induce seizures.
Yangyang Yu +4 more
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Scientific Reports, 2022 An emerging link between circadian clock function and neurodegeneration has indicated a critical role for the molecular clock in brain health. We previously reported that deletion of the core circadian clock gene Bmal1 abrogates clock function and ...
Celia A. McKee +5 more
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Astrocyte Reprogramming in Stroke: Opportunities and Challenges
Frontiers in Aging Neuroscience, 2022 Stroke is a major cause of morbidity and mortality worldwide. In the early stages of stroke, irreversible damage to neurons leads to high mortality and disability rates in patients.
Zhouzhou Peng +7 more
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The FASEB Journal, 2010 The amygdala is connected to numerous brain regions and is involved in complex behaviors such as survival and reproduction. This highly conserved brain region is sexually dimorphic in several species with the most dramatic differences found in the medial subregion.
Ryan T, Johnson +2 more
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Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes
Cells, 2019 Vimentin (VIM) is an intermediate filament (nanofilament) protein expressed in multiple cell types, including astrocytes. Mice with VIM mutations of serine sites phosphorylated during mitosis (VIMSA/SA) show cytokinetic failure in fibroblasts and lens ...
Yolanda de Pablo +6 more
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Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. [PDF]
PLoS Biology, 2012 Long-term potentiation (LTP) of synaptic transmission represents the cellular basis of learning and memory. Astrocytes have been shown to regulate synaptic transmission and plasticity.
Marta Navarrete +6 more
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, 2023 The primary analysis in this article (The astrocyte-microglia interaction forms a feedback loop to promote epilepsy in TSC patients) is based on the code ...
Zhihao Wei
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Journal of Neuroinflammation, 2023 Despite extensive astrocyte activation in patients suffering from HIV-associated neurocognitive disorders (HAND), little is known about the contribution of astrocytes to HAND neuropathology.
Jingxian Lun +10 more
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Frontiers in Aging Neuroscience, 2018 By 2050, the aging population is predicted to expand by over 100%. Considering this rapid growth, and the additional strain it will place on healthcare resources because of age-related impairments, it is vital that researchers gain a deeper understanding of the cellular interactions that occur with normal aging.
Alexandra L. Palmer +2 more
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