Results 21 to 30 of about 137,539 (311)

Laquinimod Modulates Human Astrocyte Function and Dampens Astrocyte-Induced Neurotoxicity during Inflammation [PDF]

, 2020
Astrocytes greatly participate to inflammatory and neurotoxic reactions occurring in neurodegenerative diseases and are valuable pharmacological targets to support neuroprotection.
Ottoboni, Linda, Gianvito Martino, De Angelis, Anthea, Farina, Cinthia, Colombo, Emanuela, Martino, Gianvito, Cinthia Farina, Comi, Giancarlo, Rosaria Pascente, Claudia Bassani, Francesca Ruffini, Linda Ottoboni, Pascente, Rosaria, Daniela Triolo, Anthea De Angelis, Triolo, Daniela, Ruffini, Francesca, Emanuela Colombo, Giancarlo Comi, Bassani, Claudia, Triolo D., Pascente R., De Angelis A., Comi G., Ruffini F., Ottoboni L., Farina C., Colombo E., Martino G., Bassani C.   +29 more
core   +2 more sources

wzh7768/The-astrocyte-microglia-interaction-forms-a-feedback-loop-to-promote-epilepsy-in-TSC-patients: The astrocyte-microglia interaction forms a feedback loop to promote epilepsy in TSC patients

, 2023
The primary analysis in this article (The astrocyte-microglia interaction forms a feedback loop to promote epilepsy in TSC patients) is based on the code ...
Zhihao Wei
core   +1 more source

Remodeling of astrocyte secretome in amyotrophic lateral sclerosis: uncovering novel targets to combat astrocyte-mediated toxicity [PDF]

, 2022
Amyotrophic lateral sclerosis (ALS) is an adult-onset paralytic disease characterized by progressive degeneration of upper and lower motor neurons in the motor cortex, brainstem and spinal cord.
Shi-Yan Ng, Winanto Ng, Padilla Gil, Dora Nancy, Ng, Winanto, Ng, Shi-Yan   +4 more
core   +1 more source

Porosome in astrocytes [PDF]

Journal of Cellular and Molecular Medicine, 2009
AbstractSecretion is a universal cellular process occurring in bakers yeast, to the complex multicellular organisms, to humans beings. Neurotransmission, digestion, immune response or the release of hormones occur as a result of cell secretion. Secretory defects result in numerous diseases and hence a molecular understanding of the process is critical.
Lee, Jin-Sook, Cho, Won Jin, Jeftinija, Ksenija, Jeftinija, Srdija, Jena, Bhanu P   +4 more
openaire   +2 more sources

The Neurotropic Parasite Toxoplasma gondii Induces Astrocyte Polarization Through NFκB Pathway

Frontiers in Medicine, 2019
Background:Toxoplasma gondii is a protozoan parasite that chronically infects nearly one-third of the world's human population. In immunosuppressed individuals and fetus, infection with T.
Yu Jin, Yong Yao, Saeed El-Ashram, Saeed El-Ashram, Jiaming Tian, Jilong Shen, Yongsheng Ji   +6 more
doaj   +1 more source

Astrocyte Reprogramming in Stroke: Opportunities and Challenges

Frontiers in Aging Neuroscience, 2022
Stroke is a major cause of morbidity and mortality worldwide. In the early stages of stroke, irreversible damage to neurons leads to high mortality and disability rates in patients.
Zhouzhou Peng, Zhouzhou Peng, Hui Lu, Hui Lu, Qingwu Yang, Qingwu Yang, Qi Xie, Qi Xie   +7 more
doaj   +1 more source

Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. [PDF]

PLoS Biology, 2012
Long-term potentiation (LTP) of synaptic transmission represents the cellular basis of learning and memory. Astrocytes have been shown to regulate synaptic transmission and plasticity.
Marta Navarrete, Gertrudis Perea, David Fernandez de Sevilla, Marta Gómez-Gonzalo, Angel Núñez, Eduardo D Martín, Alfonso Araque   +6 more
doaj   +1 more source

Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders

Journal of Neuroinflammation, 2023
Despite extensive astrocyte activation in patients suffering from HIV-associated neurocognitive disorders (HAND), little is known about the contribution of astrocytes to HAND neuropathology.
Jingxian Lun, Yubin Li, Xuefeng Gao, Zelong Gong, Xiaoliang Chen, Jinhu Zou, Chengxing Zhou, Yuanyuan Huang, Bingliang Zhou, Pengwei Huang, Hong Cao   +10 more
doaj   +1 more source

Astrocyte development—More questions than answers

Frontiers in Cell and Developmental Biology, 2023
The past 15–20 years has seen a remarkable shift in our understanding of astrocyte contributions to central nervous system (CNS) function. Astrocytes have emerged from the shadows of neuroscience and are now recognized as key elements in a broad array of
Kathryn M. Markey, Jillian C. Saunders, Jana Smuts, Catherine R. von Reyn, Catherine R. von Reyn, A. Denise R. Garcia, A. Denise R. Garcia   +6 more
doaj   +1 more source

HepaCAM controls astrocyte self-organization and coupling

, 2021
Astrocytes extensively infiltrate the neuropil to regulate critical aspects of synaptic development and function. This process is regulated by transcellular interactions between astrocytes and neurons via cell adhesion molecules.
Hippenmeyer, Simon, Jiang, Changyu, Savage, Justin T., Ji, Ru-Rong, Eroglu, Cagla, Elorza-Vidal, Xabier, Estévez, Raúl, Rülicke, Thomas, Strader, Samuel T., Hippenmeyer, Simon ; https://orcid.org/, Baldwin, Katherine T., Contreras, Ximena, Tan, Christabel X., Raúl Estévez, Cagla Eroglu, Christabel X. Tan, Katherine T. Baldwin, Simon Hippenmeyer, Justin T. Savage, Samuel T. Strader, Ximena Contreras, Changyu Jiang, Ru-Rong Ji, Xabier Elorza-Vidal, Thomas Rülicke   +24 more
core   +1 more source