Results 21 to 30 of about 172,284 (291)
Astrocyte polarization in glaucoma: a new opportunity
Astrocyte polarization is a new concept which is similar to microglia polarization and in which astrocytes are classified as A1 (neurotoxic) and A2 (neuroprotective).
Yi-Xin Liu, Hao Sun, Wen-Yi Guo
doaj +1 more source
Rapamycin attenuates acute seizure-induced astrocyte injury in mice in vivo [PDF]
Astrocytes have been implicated in epileptogenesis and seizure-induced brain injury. Pathological studies reveal a variety of structural abnormalities in astrocytes, such as vacuolization and astrogliosis.
Guo, Dongjun, Wong, Michael, Zou, Jia
core +2 more sources
Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes.
Simone A. van den Berge +3 more
doaj +1 more source
The Neurotropic Parasite Toxoplasma gondii Induces Astrocyte Polarization Through NFκB Pathway
Background:Toxoplasma gondii is a protozoan parasite that chronically infects nearly one-third of the world's human population. In immunosuppressed individuals and fetus, infection with T.
Yu Jin +6 more
doaj +1 more source
Astrocyte development—More questions than answers
The past 15–20 years has seen a remarkable shift in our understanding of astrocyte contributions to central nervous system (CNS) function. Astrocytes have emerged from the shadows of neuroscience and are now recognized as key elements in a broad array of
Kathryn M. Markey +6 more
doaj +1 more source
Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E. +5 more
core +1 more source
Morphological plasticity of astroglia: Understanding synaptic microenvironment [PDF]
Memory formation in the brain is thought to rely on the remodeling of synaptic connections which eventually results in neural network rewiring. This remodeling is likely to involve ultrathin astroglial protrusions which often occur in the immediate ...
Heller, JP, Rusakov, DA
core +1 more source
Astrocytes contribute to brain inflammation in neurological disorders but the molecular mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory endpoints are complex and poorly understood.
Michaela M. Novakovic +7 more
doaj +1 more source
Astrocyte as Spatiotemporal Integrating Detector of Neuronal Activity
The functional role of astrocyte calcium signaling in brain information processing was intensely debated in recent decades. This interest was motivated by high resolution imaging techniques showing highly developed structure of distal astrocyte processes.
Susan Yu. Gordleeva +3 more
doaj +1 more source
Background Neuronal damage in acute CNS injuries and chronic neurodegenerative diseases is invariably accompanied by an astrocyte reaction in both mice and humans.
Sudeshna Das +4 more
doaj +1 more source

