Results 31 to 40 of about 124,424 (305)

Astrocyte heterogeneity and interactions with local neural circuits [PDF]

, 2023
Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess many individual processes which extend out into the neuropil, where they interact with a variety of other cell types, including neurons at synapses. Astrocytes are now
Holt, MG
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Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis

Parkinson's Disease, 2012
Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes.
Simone A. van den Berge, Josta T. Kevenaar, Jacqueline A. Sluijs, Elly M. Hol   +3 more
doaj   +1 more source

The Neurotropic Parasite Toxoplasma gondii Induces Astrocyte Polarization Through NFκB Pathway

Frontiers in Medicine, 2019
Background:Toxoplasma gondii is a protozoan parasite that chronically infects nearly one-third of the world's human population. In immunosuppressed individuals and fetus, infection with T.
Yu Jin, Yong Yao, Saeed El-Ashram, Saeed El-Ashram, Jiaming Tian, Jilong Shen, Yongsheng Ji   +6 more
doaj   +1 more source

Astrocyte-Derived Lipocalin‑2 Is Involved in Mitochondrion-Related Neuronal Apoptosis Induced by Methamphetamine

, 2020
Methamphetamine (METH) is a widely abused and highly addictive psychoactive stimulant that can induce neuronal apoptosis. Lipocalin-2 (LCN2) is a member of the lipocalin family, and its upregulation is involved in cell death in the adult brain.
Xuebing Chen (708911), Huijun Wang (288634), Fu Zhang (4763397), Dongfang Qiao (7292756), Feng Qiu (496465), Jiancong Lu (7292750), Xiaohui Tan (654208), Chao Liu (43092), Chuanxiang Chen (7292753), Xu Zhao (133907), Jingtao Xu (1843699)   +10 more
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Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels

Nature Communications, 2023
Astrocytes contribute to brain inflammation in neurological disorders but the molecular mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory endpoints are complex and poorly understood.
Michaela M. Novakovic, Kirill S. Korshunov, Rogan A. Grant, Megan E. Martin, Hiam A. Valencia, G. R. Scott Budinger, Jelena Radulovic, Murali Prakriya   +7 more
doaj   +1 more source

Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex [PDF]

, 2014
Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca2+-stimulated release of various gliotransmitters, including glutamate and ATP. A physiological role of ATP release from
Lalo, Ulyana, Pankratov, Yuriy, Palygin, Oleg, Oleg Palygin (407627), Philip G Haydon, Ulyana Lalo (506296), Yuriy Pankratov, Seyed Rasooli-Nejad (506297), Rasooli-Nejad, Seyed, Yuriy Pankratov (407630), Oleg Palygin, Ulyana Lalo, Haydon, Philip G., Jemma Andrew, Jemma Andrew (506298), Philip G. Haydon (506299), Andrew, Jemma, Seyed Rasooli-Nejad   +17 more
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Novel cell separation method for molecular analysis of neuron-astrocyte cocultures

Frontiers in Cellular Neuroscience, 2014
Over the last decade, the importance of astrocyte-neuron communication in neuronal development and synaptic plasticity has become increasingly clear. Since neuron-astrocyte interactions represent highly dynamic and reciprocal processes, we hypothesized ...
Andrea eGoudriaan, Nutabi eCamargo, Karen eCarney, Karen eCarney, Karen eCarney, Stéphane H.R. Oliet, Stéphane H.R. Oliet, August B. Smit, Mark H.G. Verheijen   +8 more
doaj   +1 more source

Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes

, 2005
Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes, which in ...
Heloise West, Richardson, WD, West, H, William D. Richardson, Fruttiger, M, Marcus Fruttiger   +5 more
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Model of astrocyte ensheathment.

, 2023
A: Schematic of astrocyte (purple) ensheathment of a synapse (blue). The astrocyte is protruding into the synaptic cleft by amount ϕ. B: Time course of receptor activation in a diffusion with recharging traps simulation for different depths of astrocyte ...
Gregory Handy (4903174), Alla Borisyuk (4903177)   +1 more
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FGFR3-TACC3 fusion as a potential primary resistance mechanism to EGFR-TKI in lung adenocarcinoma harboring co-driven mutations: a case report

Frontiers in Oncology
Oncogenic driver mutations were once considered mutually exclusive in non-small cell lung cancer (NSCLC), and the optimal management for these patients with co-mutations of driver genes remains controversial.
Xiuwen Wang, Liwen Qiu, Jizhen Liang, Fei Liu, Xiaoxue Ma, Pan Yang   +5 more
doaj   +1 more source