Results 31 to 40 of about 172,284 (291)

An efficient platform for astrocyte differentiation from human induced pluripotent stem cells [PDF]

, 2017
Summary: Growing evidence implicates the importance of glia, particularly astrocytes, in neurological and psychiatric diseases. Here, we describe a rapid and robust method for the differentiation of highly pure populations of replicative astrocytes from ...
Abdelaal, Rawan, Bowles, Kathryn R, Brennand, Kristen J, Goate, Alison M, Hartley, Brigham J, Karch, Celeste M, Lacin, Emre, Machlovi, Saima I, Phatnani, Hemali, Pimenova, Anna A, Slesinger, Paul A, TCW, Julia, Wang, Minghui, Zhang, Bin   +13 more
core   +3 more sources

Novel cell separation method for molecular analysis of neuron-astrocyte cocultures

Frontiers in Cellular Neuroscience, 2014
Over the last decade, the importance of astrocyte-neuron communication in neuronal development and synaptic plasticity has become increasingly clear. Since neuron-astrocyte interactions represent highly dynamic and reciprocal processes, we hypothesized ...
Andrea eGoudriaan, Nutabi eCamargo, Karen eCarney, Karen eCarney, Karen eCarney, Stéphane H.R. Oliet, Stéphane H.R. Oliet, August B. Smit, Mark H.G. Verheijen   +8 more
doaj   +1 more source

Ammonia toxicity: from head to toe? [PDF]

, 2016
Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan, Mookerjee, Rajeshwar P., Ott, Peter, Rackayova, Veronika, Rangroo Thrane, Vinita, Rose, Christopher, Vairappan, Balasubramaniyan   +6 more
core   +1 more source

FGFR3-TACC3 fusion as a potential primary resistance mechanism to EGFR-TKI in lung adenocarcinoma harboring co-driven mutations: a case report

Frontiers in Oncology
Oncogenic driver mutations were once considered mutually exclusive in non-small cell lung cancer (NSCLC), and the optimal management for these patients with co-mutations of driver genes remains controversial.
Xiuwen Wang, Liwen Qiu, Jizhen Liang, Fei Liu, Xiaoxue Ma, Pan Yang   +5 more
doaj   +1 more source

CCAAT/enhancer binding protein β expression is increased in the brain during HIV-1-infection and contributes to regulation of astrocyte tissue inhibitor of metalloproteinase-1 [PDF]

, 2011
Human immunodeficiency virus (HIV)-1-associated neurocognitive disorders (HAND) associated with infection and activation of mononuclear phagocytes (MP) in the brain, occur late in disease. Infected/activated MP initiate neuroinflammation activating glial
Abraham, Akira, Alberini, Albertini, Borjabad, Brambilla, Brambilla, Bugno, Cardinaux, Chaillan, Chen, Clark, Cortes-Canteli, Crocker, Dean, Dean, Dhar, Ejarque-Ortiz, Fassina, Faulkner, Ferrari, Ferrari, Gardner, Gardner, Gris, Heales, Herrmann, Hornebeck, Jaworski, Jourquin, La Fleur, Laird, Lindl, Liu, Lorenzl, Lorenzl, Lorenzl, Manthrope, Menard, Nadeau, Oberheim, Ould-yahoui, Pagenstecher, Panenka, Phillips, Rivera, Sandhir, Sears, Sofroniew, Sofroniew, Sterneck, Suryadevara, Yadav, Yong, Yukawa   +54 more
core   +1 more source

Effects of 660-nm LED photobiomodulation on drebrin expression pattern and astrocyte migration

Scientific Reports, 2023
Photobiomodulation (PBM) is a therapeutic tool that uses red or near-infrared light in medical applications. It’s applications in both central (CNS) and peripheral nervous system (PNS) are widely studied.
Sung Ryeong Yoon, So-Young Chang, Min Young Lee, Jin-Chul Ahn   +3 more
doaj   +1 more source

Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence [PDF]

, 2015
Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined.
Arakaki, Naomi, Fernandez Espinosa, Damian Dario, Garcia, Carolina Paola, Martinetto, Horacio Enrique, Miriuka, Santiago Gabriel, Roisman, Alejandro, Romorini, Leonardo, Scassa, Maria Elida, Sevlever, Gustavo Emilio, Slavutsky, Irma Rosa, Videla Richardson, Guillermo Agustín   +10 more
core   +1 more source

Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma

Frontiers in Pharmacology
BackgroundTumor metabolism reprogramming is a hallmark of cancer, but metabolite-mediated intercellular communication remains poorly understood. To address this gap, we estimated and explored communication events exploring based on single‐cell RNA data ...
Qiang Liu, Huiguo Chen, Dongfang Tang, Huibiao Zhang, Shaogeng Chen, Yiran Meng, Boying Zheng, Fei Liu, Jing Zhou, Wen Zhang   +9 more
doaj   +1 more source

Non-aggregated Aβ25-35 Upregulates Primary Astrocyte Proliferation In Vitro

Frontiers in Cellular Neuroscience, 2017
Amyloid beta (Aβ) is a peptide cleaved from amyloid precursor protein that contributes to the formation of senile plaques in Alzheimer’s disease (AD). The relationship between Aβ and astrocyte proliferation in AD remains controversial.
Elise C. Ohki, Thomas J. Langan, Thomas J. Langan, Kyla R. Rodgers, Richard C. Chou, Richard C. Chou   +5 more
doaj   +1 more source

Self-determination theory applied to Dark Souls: fostering motivation in video game communities

Interacciones
Background: Video games have emerged as a significant field of study in psychology, particularly in understanding human motivation. Self-Determination Theory (SDT) posits that human motivation is driven by three basic psychological needs: autonomy ...
Fritz Fidel Váscones-Román, Diego Alonso Quiroz-Marcelo, Diana Karina Común-Gutierrez, Diego Fernando Sanchez-Torres, Franz Jair Vera-Arias   +4 more
doaj   +1 more source