Results 31 to 40 of about 137,539 (311)
Model of astrocyte ensheathment.
, 2023 A: Schematic of astrocyte (purple) ensheathment of a synapse (blue). The astrocyte is protruding into the synaptic cleft by amount ϕ. B: Time course of receptor activation in a diffusion with recharging traps simulation for different depths of astrocyte ...
Gregory Handy (4903174) +1 more
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Frontiers in Aging Neuroscience, 2018 By 2050, the aging population is predicted to expand by over 100%. Considering this rapid growth, and the additional strain it will place on healthcare resources because of age-related impairments, it is vital that researchers gain a deeper understanding of the cellular interactions that occur with normal aging.
Alexandra L. Palmer +2 more
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Frontiers in OncologyOncogenic driver mutations were once considered mutually exclusive in non-small cell lung cancer (NSCLC), and the optimal management for these patients with co-mutations of driver genes remains controversial.
Xiuwen Wang +5 more
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Nature Communications, 2023 Astrocytes contribute to brain inflammation in neurological disorders but the molecular mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory endpoints are complex and poorly understood.
Michaela M. Novakovic +7 more
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Astrocyte polarization in glaucoma: a new opportunity
Neural Regeneration Research, 2022 Astrocyte polarization is a new concept which is similar to microglia polarization and in which astrocytes are classified as A1 (neurotoxic) and A2 (neuroprotective).
Yi-Xin Liu, Hao Sun, Wen-Yi Guo
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Ompa Is the Critical Component for Escherichia Coli Invasion-Induced Astrocyte Activation
, 2010 Escherichia coli is the major Gram-negative bacterial pathogen in neonatal meningitis. Outer membrane protein A ( OmpA) is a conserved major protein in the E. coli outer membrane and is involved in several host- cell interactions.
WU, HSUEH-HSIA;YANG, YI-YUAN;HSIEH, WEN -SHYANG;LEU, SY-JYE;CHEN, MEI-RU +1 more
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, 2020 Methamphetamine (METH) is a widely abused and highly addictive psychoactive stimulant that can induce neuronal apoptosis. Lipocalin-2 (LCN2) is a member of the lipocalin family, and its upregulation is involved in cell death in the adult brain.
Xuebing Chen (708911) +10 more
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Astrocyte as Spatiotemporal Integrating Detector of Neuronal Activity
Frontiers in Physiology, 2019 The functional role of astrocyte calcium signaling in brain information processing was intensely debated in recent decades. This interest was motivated by high resolution imaging techniques showing highly developed structure of distal astrocyte processes.
Susan Yu. Gordleeva +3 more
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NeuronThe mammalian nervous system is impacted by aging. Aging alters brain architecture, is associated with molecular damage, and can manifest with cognitive and motor deficits that diminish the quality of life. Astrocytes are glial cells of the CNS that regulate the development, function, and repair of neural circuits during development and adulthood ...
Lara Labarta-Bajo, Nicola J. Allen
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Mechanosensory Signaling in Astrocytes [PDF]
The Journal of Neuroscience, 2020 Mechanosensitivity is a well-known feature of astrocytes, however, its underlying mechanisms and functional significance remain unclear. There is evidence that astrocytes are acutely sensitive to decreases in cerebral perfusion pressure and may function as intracranial baroreceptors, tuned to monitor brain blood flow.
Egor A. Turovsky +12 more
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