Results 51 to 60 of about 133,591 (301)
Journal of Neuroinflammation, 2020 Background Neuronal damage in acute CNS injuries and chronic neurodegenerative diseases is invariably accompanied by an astrocyte reaction in both mice and humans.
Sudeshna Das +4 more
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Ompa Is the Critical Component for Escherichia Coli Invasion-Induced Astrocyte Activation
, 2010 Escherichia coli is the major Gram-negative bacterial pathogen in neonatal meningitis. Outer membrane protein A ( OmpA) is a conserved major protein in the E. coli outer membrane and is involved in several host- cell interactions.
WU, HSUEH-HSIA;YANG, YI-YUAN;HSIEH, WEN -SHYANG;LEU, SY-JYE;CHEN, MEI-RU +1 more
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Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine [PDF]
, 2012 Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is ...
Schmitt, L. Ian +9 more
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Novel cell separation method for molecular analysis of neuron-astrocyte cocultures
Frontiers in Cellular Neuroscience, 2014 Over the last decade, the importance of astrocyte-neuron communication in neuronal development and synaptic plasticity has become increasingly clear. Since neuron-astrocyte interactions represent highly dynamic and reciprocal processes, we hypothesized ...
Andrea eGoudriaan +8 more
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Model of astrocyte ensheathment.
, 2023 A: Schematic of astrocyte (purple) ensheathment of a synapse (blue). The astrocyte is protruding into the synaptic cleft by amount ϕ. B: Time course of receptor activation in a diffusion with recharging traps simulation for different depths of astrocyte ...
Gregory Handy (4903174) +1 more
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NeuronThe mammalian nervous system is impacted by aging. Aging alters brain architecture, is associated with molecular damage, and can manifest with cognitive and motor deficits that diminish the quality of life. Astrocytes are glial cells of the CNS that regulate the development, function, and repair of neural circuits during development and adulthood ...
Lara Labarta-Bajo, Nicola J. Allen
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Mechanosensory Signaling in Astrocytes [PDF]
The Journal of Neuroscience, 2020 Mechanosensitivity is a well-known feature of astrocytes, however, its underlying mechanisms and functional significance remain unclear. There is evidence that astrocytes are acutely sensitive to decreases in cerebral perfusion pressure and may function as intracranial baroreceptors, tuned to monitor brain blood flow.
Egor A. Turovsky +12 more
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Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma
Frontiers in PharmacologyBackgroundTumor metabolism reprogramming is a hallmark of cancer, but metabolite-mediated intercellular communication remains poorly understood. To address this gap, we estimated and explored communication events exploring based on single‐cell RNA data ...
Qiang Liu +9 more
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Self-determination theory applied to Dark Souls: fostering motivation in video game communities
InteraccionesBackground: Video games have emerged as a significant field of study in psychology, particularly in understanding human motivation. Self-Determination Theory (SDT) posits that human motivation is driven by three basic psychological needs: autonomy ...
Fritz Fidel Váscones-Román +4 more
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Journal of Integrative Neuroscience, 2022 The cellular, molecular and physiological basis of cognition has proved elusive until emerging studies on astrocytes. The appearance of a deliberate aggregating element in cellular neurophysiology was difficult to satisfy computationally with excitatory and inhibitory neuron physiology alone.
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