Results 41 to 50 of about 124,424 (305)
Journal of Neuroinflammation, 2020 Background Neuronal damage in acute CNS injuries and chronic neurodegenerative diseases is invariably accompanied by an astrocyte reaction in both mice and humans.
Sudeshna Das +4 more
doaj +1 more source
Microfluidic device to study spatial and temporal response of astrocyte networks in response to changes in the biochemical milieu. [PDF]
Microsyst NanoengAstrocytes are the most abundant cell type in the central nervous system and are major players in brain homeostasis and inflammation. Astrocytes form a syncytial three-dimensional (3D) network across the brain tissue.
Reed-McBain CA +13 more
europepmc +2 more sources
Ompa Is the Critical Component for Escherichia Coli Invasion-Induced Astrocyte Activation
, 2010 Escherichia coli is the major Gram-negative bacterial pathogen in neonatal meningitis. Outer membrane protein A ( OmpA) is a conserved major protein in the E. coli outer membrane and is involved in several host- cell interactions.
WU, HSUEH-HSIA;YANG, YI-YUAN;HSIEH, WEN -SHYANG;LEU, SY-JYE;CHEN, MEI-RU +1 more
core +1 more source
Astrocyte activation in neurovascular damage and repair following ischaemic stroke
, 2021 Transient or permanent loss of tissue perfusion due to ischaemic stroke can lead to damage to the neurovasculature, and disrupt brain homeostasis, causing long-term motor and cognitive deficits. Despite promising pre-clinical studies, clinically approved
Patabendige, A.
core +1 more source
Astrocyte-neuron circuits in epilepsy
, 2023 The epilepsies are a diverse spectrum of disease states characterized by spontaneous seizures and associated comorbidities. Neuron-focused perspectives have yielded an array of widely used anti-seizure medications and are able to explain some, but not ...
Benton S Purnell (14801967) +2 more
core
Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine [PDF]
, 2012 Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is ...
Schmitt, L. Ian +9 more
core +1 more source
Astrocyte as Spatiotemporal Integrating Detector of Neuronal Activity
Frontiers in Physiology, 2019 The functional role of astrocyte calcium signaling in brain information processing was intensely debated in recent decades. This interest was motivated by high resolution imaging techniques showing highly developed structure of distal astrocyte processes.
Susan Yu. Gordleeva +3 more
doaj +1 more source
NeuronThe mammalian nervous system is impacted by aging. Aging alters brain architecture, is associated with molecular damage, and can manifest with cognitive and motor deficits that diminish the quality of life. Astrocytes are glial cells of the CNS that regulate the development, function, and repair of neural circuits during development and adulthood ...
Lara Labarta-Bajo, Nicola J. Allen
openaire +2 more sources
Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma
Frontiers in PharmacologyBackgroundTumor metabolism reprogramming is a hallmark of cancer, but metabolite-mediated intercellular communication remains poorly understood. To address this gap, we estimated and explored communication events exploring based on single‐cell RNA data ...
Qiang Liu +9 more
doaj +1 more source
Effects of 660-nm LED photobiomodulation on drebrin expression pattern and astrocyte migration
Scientific Reports, 2023 Photobiomodulation (PBM) is a therapeutic tool that uses red or near-infrared light in medical applications. It’s applications in both central (CNS) and peripheral nervous system (PNS) are widely studied.
Sung Ryeong Yoon +3 more
doaj +1 more source