Results 11 to 20 of about 137,539 (311)
eLife, 2016 Interneurons are critical for proper neural network function and can activate Ca2+ signaling in astrocytes. However, the impact of the interneuron-astrocyte signaling into neuronal network operation remains unknown.
Gertrudis Perea +18 more
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Acute treatment with 17β-estradiol attenuates astrocyte-astrocyte and astrocyte-neuron communication
Glia, 2007 Astrocytes are now recognized as dynamic signaling elements in the brain. Bidirectional communication between neurons and astrocytes involves integration of neuronal inputs by astrocytes and release of gliotransmitters that modulate neuronal excitability
Rao, Shilpa P., Sikdar, Sujit Kumar
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Exocytosis in Astrocytes [PDF]
Biomolecules, 2021 Until recently, astrocytes were thought to be a part of a simple “brain glue” providing only a supporting role for neurons. However, the discoveries of the last two decades have proven astrocytes to be dynamic partners participating in brain metabolism and actively influencing communication between neurons.
Aleksandra Mielnicka, Piotr Michaluk
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Neurotherapeutics, 2010 Astrocytes form a significant constituent of seizure foci in the human brain. For a long time it was believed that astrocytes play a significant role in the causation of seizures. With the increase in our understanding of the unique biology of these cells, their precise role in seizure foci is receiving renewed attention.
Nihal C, de Lanerolle +2 more
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The Synucleins and the Astrocyte
Biology, 2023 Synucleins consist of three proteins exclusively expressed in vertebrates. α-Synuclein (αS) has been identified as the main proteinaceous aggregate in Lewy bodies, a pathological hallmark of many neurodegenerative diseases. Less is understood about β-synuclein (βS) and γ-synuclein (γS), although it is known βS can interact with αS in vivo to inhibit ...
Abigail J. Myers +3 more
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Astrocytes in schizophrenia [PDF]
Brain and Neuroscience Advances, 2021 Schizophrenia is a severe and clinically heterogenous mental disorder affecting approximately 1% of the population worldwide. Despite tremendous achievements in the field of schizophrenia research, its precise aetiology remains elusive. Besides dysfunctional neuronal signalling, the pathophysiology of schizophrenia appears to involve molecular and ...
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Short-term memory in neuron-astrocyte network [PDF]
, 2020 In this paper, we study the role of astrocyte-induced modulation of signal transmission in network of synaptically coupled spiking neurons in the mechanisms of the short-term memory formation.
Gorban, A +9 more
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Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes [PDF]
, 2005 Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes, which in ...
Heloise West +5 more
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Astrocytes in Tauopathies [PDF]
Frontiers in Neurology, 2020 Tauopathies are a group of neurodegenerative diseases characterized by the progressive accumulation across the brain of hyperphosphorylated aggregates of the microtubule-associated protein tau that vary in isoform composition, structural conformation and localization.
Reid, Matt +4 more
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Progress in Neurobiology, 2008 Neurons have long held the spotlight as the central players of the nervous system, but we must remember that we have equal numbers of astrocytes and neurons in the brain. Are these cells only filling up the space and passively nurturing the neurons, or do they also contribute to information transfer and processing?
Doris D, Wang, Angélique, Bordey
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