Results 11 to 20 of about 133,591 (301)
Trends in Cell Biology, 2023 Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal feature of astrocytes is their complex and visually enchanting morphology, referred to as bushy, spongy, and star-like. A central precept of this review is that
Keith K. Murai +5 more
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Pharmacological activation of cGMP signaling promotes astrocyte remodeling and enrichment of perivascular GLUT1 in the murine retina [PDF]
Frontiers in Cellular NeuroscienceAstrocytes regulate metabolic exchange between the vasculature and neurons in the central nervous system (CNS). In the retina of the eye, also a component of the CNS, astrocyte endfeet couple to vascular elements to mediate glucose uptake via the glucose
Kristin L. Clark +6 more
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A spatial threshold for astrocyte calcium surge
eLifeAstrocytes are active cells involved in brain function through the bidirectional communication with neurons, in which astrocyte calcium plays a crucial role.
Justin Lines +7 more
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eLife, 2016 Interneurons are critical for proper neural network function and can activate Ca2+ signaling in astrocytes. However, the impact of the interneuron-astrocyte signaling into neuronal network operation remains unknown.
Gertrudis Perea +18 more
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Astrocyte polarization in glaucoma: a new opportunity
Neural Regeneration Research, 2022 Astrocyte polarization is a new concept which is similar to microglia polarization and in which astrocytes are classified as A1 (neurotoxic) and A2 (neuroprotective).
Yi-Xin Liu, Hao Sun, Wen-Yi Guo
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Acute treatment with 17β-estradiol attenuates astrocyte-astrocyte and astrocyte-neuron communication
Glia, 2007 Astrocytes are now recognized as dynamic signaling elements in the brain. Bidirectional communication between neurons and astrocytes involves integration of neuronal inputs by astrocytes and release of gliotransmitters that modulate neuronal excitability
Rao, Shilpa P., Sikdar, Sujit Kumar
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Astrocyte store-operated calcium entry is required for centrally mediated neuropathic pain [PDF]
PAIN Reports. Introduction:. Acute injuries transition to chronic neuropathic pain through central sensitization (CS), which involves plastic changes to nociceptive networks within the central nervous system.
Mariya A. Prokhorenko, Jeremy T. Smyth
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Exocytosis in Astrocytes [PDF]
Biomolecules, 2021 Until recently, astrocytes were thought to be a part of a simple “brain glue” providing only a supporting role for neurons. However, the discoveries of the last two decades have proven astrocytes to be dynamic partners participating in brain metabolism and actively influencing communication between neurons.
Aleksandra Mielnicka, Piotr Michaluk
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Neurotherapeutics, 2010 Astrocytes form a significant constituent of seizure foci in the human brain. For a long time it was believed that astrocytes play a significant role in the causation of seizures. With the increase in our understanding of the unique biology of these cells, their precise role in seizure foci is receiving renewed attention.
Nihal C, de Lanerolle +2 more
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The Synucleins and the Astrocyte
Biology, 2023 Synucleins consist of three proteins exclusively expressed in vertebrates. α-Synuclein (αS) has been identified as the main proteinaceous aggregate in Lewy bodies, a pathological hallmark of many neurodegenerative diseases. Less is understood about β-synuclein (βS) and γ-synuclein (γS), although it is known βS can interact with αS in vivo to inhibit ...
Abigail J. Myers +3 more
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