Results 11 to 20 of about 124,424 (305)
Neurotherapeutics, 2010 Astrocytes form a significant constituent of seizure foci in the human brain. For a long time it was believed that astrocytes play a significant role in the causation of seizures. With the increase in our understanding of the unique biology of these cells, their precise role in seizure foci is receiving renewed attention.
Nihal C, de Lanerolle +2 more
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Cells, 2022 Astrocytes have many important functions in the brain, but their roles in psychiatric disorders and their responses to psychotropic medications are still being elucidated.
Xiaolu Zhang +10 more
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Response of Astrocyte Subpopulations Following Spinal Cord Injury
Cells, 2022 There is growing appreciation for astrocyte heterogeneity both across and within central nervous system (CNS) regions, as well as between intact and diseased states. Recent work identified multiple astrocyte subpopulations in mature brain. Interestingly,
R. Vivian Allahyari +9 more
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Molecular Neurodegeneration, 2023 Background Previous studies show that antibiotic-mediated (abx) alteration of the gut microbiome (GMB) results in a reduction of amyloid beta (Aβ) plaques and proinflammatory microglial phenotype in male APPPS1-21 mice.
Sidhanth Chandra +9 more
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Molecular Brain, 2021 The morphological dynamics of astrocytes are altered in the hippocampus during memory induction. Astrocyte–neuron interactions on synapses are called tripartite synapses. These control the synaptic function in the central nervous system.
Moonseok Choi +5 more
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Progress in Neurobiology, 2008 Neurons have long held the spotlight as the central players of the nervous system, but we must remember that we have equal numbers of astrocytes and neurons in the brain. Are these cells only filling up the space and passively nurturing the neurons, or do they also contribute to information transfer and processing?
Doris D, Wang, Angélique, Bordey
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Adenosine-independent regulation of the sleep–wake cycle by astrocyte activity
Cell Discovery, 2023 Astrocytes play a crucial role in regulating sleep–wake behavior, and adenosine signaling is generally thought to be involved. Here we show multiple lines of evidence supporting that modulation of the sleep–wake behavior by astrocyte Ca2+ activity could ...
Wanling Peng +10 more
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The Synucleins and the Astrocyte
Biology, 2023 Synucleins consist of three proteins exclusively expressed in vertebrates. α-Synuclein (αS) has been identified as the main proteinaceous aggregate in Lewy bodies, a pathological hallmark of many neurodegenerative diseases. Less is understood about β-synuclein (βS) and γ-synuclein (γS), although it is known βS can interact with αS in vivo to inhibit ...
Abigail J. Myers +3 more
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Journal of Cellular and Molecular Medicine, 2009 AbstractSecretion is a universal cellular process occurring in bakers yeast, to the complex multicellular organisms, to humans beings. Neurotransmission, digestion, immune response or the release of hormones occur as a result of cell secretion. Secretory defects result in numerous diseases and hence a molecular understanding of the process is critical.
Lee, Jin-Sook +4 more
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Glutamate mediated astrocytic filtering of neuronal activity. [PDF]
PLoS Computational Biology, 2014 Neuron-astrocyte communication is an important regulatory mechanism in various brain functions but its complexity and role are yet to be fully understood.
Gilad Wallach +6 more
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