Results 41 to 50 of about 158,206 (306)

Palmitoylethanolamide dampens reactive astrogliosis and improves neuronal trophic support in a triple transgenic model of Alzheimer’s disease: in vitro and in vivo evidence [PDF]

, 2018
Alzheimer’s disease (AD) is a neurodegenerative disorder responsible for the majority of dementia cases in elderly people. It is widely accepted that the main hallmarks of AD are not only senile plaques and neurofibrillary tangles but also reactive ...
Bronzuoli, MARIA ROSANNA, Cassano, Tommaso, Facchinetti, Roberta, Passarella, Sergio, Romano, Adele, Scuderi, Caterina, Steardo Jr, Luca, Steardo, Luca, Stecca, Claudia   +8 more
core   +3 more sources

The influence of acelysin and nimotop on the cellular response of the hippocampus during the dynamics of experimental subarachnoid hemorrhage

Patologìâ, 2023
Aim. Immunohistochemical study of rat hippocampal neurons and astrocytes at different time-points of experimental brain hemorrhage treated with acelysin and nimotop. Materials and methods. Subarachnoid hemorrhage (SAH) was modeled according to R.
O. Yu. Polkovnikov, S. I. Tertyshnyi
doaj   +1 more source

The role of GFAP and vimentin in learning and memory [PDF]

Biological Chemistry, 2019
Abstract Intermediate filaments (also termed nanofilaments) are involved in many cellular functions and play important roles in cellular responses to stress. The upregulation of glial fibrillary acidic protein (GFAP) and vimentin (Vim), intermediate filament proteins of astrocytes, is the hallmark of astrocyte activation and reactive ...
Wilhelmsson, Ulrika, Pozo-Rodrigalvarez, Andrea, Kalm, Marie, de Pablo, Yolanda, Widestrand, Åsa, Pekna, Marcela, Pekny, Milos   +6 more
openaire   +2 more sources

Ectomesenchymal chondromyxoid tumor: A rare case report

Annals of Medical Science and Research
Ectomesenchymal chondromyxoid tumor is a very rare tumor, which mostly occurs in the tongue. Here, we are presenting a case of a 55-year-old man with a swelling in the anterior dorsum of his tongue.
Anindita Mondal, Ayesha Afreen Islam, Keya Basu, Uttara Chatterjee   +3 more
doaj   +1 more source

Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific [PDF]

, 2015
Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells.
Ali, RR, Barber, AC, Graca, AB, Hippert, C, Pearson, RA, Smith, AJ, West, EL   +6 more
core   +1 more source

Morphometric evaluation of the astrocytes reactivity in preterm and term infants with infectious diseases

Журнал инфектологии, 2014
Objective: the aim of our work is to describe a condition of the reactive astrocytes in the white matter in preterm and term infants with infectious diseases.Materials and methods: postmortem investigation of periventricular white matter performed on ...
S. V. Barashkova
doaj   +1 more source

Loss of Immunohistochemical Reactivity in Association With Handling-Induced Dark Neurons in Mouse Brains. [PDF]

, 2020
The handling-induced dark neuron is a histological artifact observed in brain samples handled before fixation with aldehydes. To explore associations between dark neurons and immunohistochemical alterations in mouse brains, we examined protein products ...
Chang, Rachel C, Jeste, Dilip V, Patel, Hemal H, Schilling, Jan M, Soontornniyomkij, Benchawanna, Soontornniyomkij, Virawudh   +5 more
core  

Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury [PDF]

, 2018
Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. Single blood biomarkers, such
Bustamante, Alejandro, Egea Guerrero, Juan José, El Rahal, Amir, García-Armengol, Roser, Lagerstedt, Linnéa, Melinda Prica, Carmen, Montaner, Joan, Quintana-Díaz, Manuel, Rodríguez Rodríguez, Ana   +8 more
core   +1 more source

Enteric Glia: S100, GFAP, and Beyond [PDF]

The Anatomical Record, 2019
ABSTRACTSince several years, the enteric nervous system (ENS) is getting more and more in the focus of gastrointestinal research. While the main interest was credited for years to the enteric neurons and their functional properties, less attention has been paid on the enteric glial cells (EGCs). Although the similarity of EGCs to central nervous system
David Grundmann, Eva Loris, Silke Maas‐Omlor, Wenhui Huang, Anja Scheller, Frank Kirchhoff, Karl‐Herbert Schäfer   +6 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source