Results 1 to 10 of about 23,298,365 (315)

Chemodivergent photocatalytic access to 1-pyrrolines and 1-tetralones involving switchable C(sp3)–H functionalization

Frontiers in Chemistry, 2022
A chemodivergent photocatalytic approach to 1-pyrrolines and 1-tetralones from alkyl bromides and vinyl azides has been developed through chemoselectively controllable intermolecular [3 + 2] and [4 + 2] cyclization.
Shijing Tu, Zhongyu Qi, Weicai Li, Shiqi Zhang, Zhijie Zhang, Jun Wei, Lin Yang, Siping Wei, Xi Du, Dong Yi   +9 more
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Central Nervous System Tuberculosis [PDF]

Baylor University Medical Center Proceedings, 2010
Central nervous system tuberculosis is a rare presentation of active tuberculosis and accounts for about 1% of cases (1). The three clinical categories include meningitis, intracranial tuberculomas, and spinal tuberculous arachnoiditis. We report a case of a young man who presented with active pulmonary tuberculosis in addition to tuberculous ...
Vincent C, Kuo, Louis M, Sloan, Michael, Emmett   +2 more
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TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAF V600E /TERT promoter double-mutated glioma

Acta Neuropathologica Communications, 2019
The BRAF gene and the TERT promoter are among the most frequently altered genomic loci in low-grade (LGG) and high-grade-glioma (HGG), respectively.
Lisa Gabler, Daniela Lötsch, Dominik Kirchhofer, Sushilla van Schoonhoven, Hannah M. Schmidt, Lisa Mayr, Christine Pirker, Katharina Neumayer, Carina Dinhof, Lucia Kastler, Amedeo A. Azizi, Christian Dorfer, Thomas Czech, Christine Haberler, Andreas Peyrl, Rajiv Kumar, Irene Slavc, Sabine Spiegl-Kreinecker, Johannes Gojo, Walter Berger   +19 more
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Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons

Molecular Brain, 2021
Somatostatin-expressing interneurons (SOM-INs) are a major subpopulation of GABAergic cells in CA1 hippocampus that receive excitation from pyramidal cells (PCs), and, in turn, provide feedback inhibition onto PC dendrites.
Anne-Sophie Racine, François-Xavier Michon, Isabel Laplante, Jean-Claude Lacaille   +3 more
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miR-19a/b promote EMT and proliferation in glioma cells via SEPT7-AKT-NF-κB pathway

Molecular Therapy: Oncolytics, 2021
miR-19a/b belong to the miR-17-92 family. We have demonstrated previously that miR-19a/b are overexpressed in glioma and glioma cell lines. However, the role of miR-19a/b in glioma remains unclear.
Weihan Wang, Yubing Hao, Anling Zhang, Weidong Yang, Wei Wei, Guangxiu Wang, Zhifan Jia   +6 more
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Use of a compact high-definition two-dimensional exoscope in surgical treatment of large vestibular schwannoma

Chinese Medical Journal, 2020
. Background:. Extra-corporeal video telescope operating monitor system provides a necessary instrument to perform high-precision neurosurgical procedures that could substitute or supplement the traditional surgical microscope.
Xin Chen, Xiang-Liang Gao, Yan Chai, Ming-Ming Shi, Jian-Ning Zhang, Shu-Yuan Yue, Xiu-Yuan Hao   +6 more
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Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

European Journal of Histochemistry, 2015
Tissue fixation is critical for immunohistochemistry. Recently, we developed a zinc-ethanol-formalin fixative (ZEF), and the present study was aimed to assess the applicability of the ZEF for the human brain histology and immunohistochemistry and to ...
D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev   +3 more
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Inhibition of neutrophil extracellular trap formation attenuates NLRP1-dependent neuronal pyroptosis via STING/IRE1α pathway after traumatic brain injury in mice

Frontiers in Immunology, 2023
IntroductionIncreased neutrophil extracellular trap (NET) formation has been reported to be associated with cerebrovascular dysfunction and neurological deficits in traumatic brain injury (TBI).
Yiyao Cao, Yiyao Cao, Yiyao Cao, Mingming Shi, Mingming Shi, Mingming Shi, Liang Liu, Liang Liu, Liang Liu, Yan Zuo, Haoran Jia, Haoran Jia, Haoran Jia, Xiaobin Min, Xilei Liu, Xilei Liu, Xilei Liu, Zhijuan Chen, Zhijuan Chen, Zhijuan Chen, Yuan Zhou, Yuan Zhou, Yuan Zhou, Shenghui Li, Shenghui Li, Shenghui Li, Guili Yang, Guili Yang, Guili Yang, Xiao Liu, Xiao Liu, Xiao Liu, Quanjun Deng, Quanjun Deng, Quanjun Deng, Fanglian Chen, Fanglian Chen, Xin Chen, Xin Chen, Xin Chen, Shu Zhang, Shu Zhang, Shu Zhang, Jianning Zhang, Jianning Zhang, Jianning Zhang   +45 more
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Coronaviruses and the central nervous system [PDF]

Journal of NeuroVirology, 2020
Seven coronavirus (CoV) species are known human pathogens: the epidemic viruses SARS-CoV, SARS-CoV-2, and MERS-CoV and those continuously circulating in human populations since initial isolation: HCoV-OC43, HCoV-229E, HCoV-HKU1, and HCoV-NL63. All have associations with human central nervous system (CNS) dysfunction.
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Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

Frontiers in Immunology, 2021
Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu, Huiming Zhang, Tian-Xiang Zhang, Meng Yuan, Chen Du, Pei Zeng, Zhenning Huang, Dongmei Jia, Guili Yang, Fu-Dong Shi, Fu-Dong Shi, Chao Zhang, Chao Zhang   +12 more
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