Results 11 to 20 of about 46,309 (120)

A Protective Role of Tumor Necrosis Factor Superfamily-15 in Intracerebral Hemorrhage-Induced Secondary Brain Injury

ASN Neuro, 2021
Destabilization of blood vessels by the activities of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) following intracerebral hemorrhage (ICH) has been considered the main causes of aggravated secondary brain injury.
Gui-Li Yang, Shizhao Wang, Shu Zhang, Ye Liu, Xiao Liu, Dong Wang, Huijie Wei, Jianhua Xiong, Zhi-Song Zhang, Zengguang Wang, Lu-Yuan Li, Jianning Zhang   +11 more
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Chemodivergent photocatalytic access to 1-pyrrolines and 1-tetralones involving switchable C(sp3)–H functionalization

Frontiers in Chemistry, 2022
A chemodivergent photocatalytic approach to 1-pyrrolines and 1-tetralones from alkyl bromides and vinyl azides has been developed through chemoselectively controllable intermolecular [3 + 2] and [4 + 2] cyclization.
Shijing Tu, Zhongyu Qi, Weicai Li, Shiqi Zhang, Zhijie Zhang, Jun Wei, Lin Yang, Siping Wei, Xi Du, Dong Yi   +9 more
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TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAF V600E /TERT promoter double-mutated glioma

Acta Neuropathologica Communications, 2019
The BRAF gene and the TERT promoter are among the most frequently altered genomic loci in low-grade (LGG) and high-grade-glioma (HGG), respectively.
Lisa Gabler, Daniela Lötsch, Dominik Kirchhofer, Sushilla van Schoonhoven, Hannah M. Schmidt, Lisa Mayr, Christine Pirker, Katharina Neumayer, Carina Dinhof, Lucia Kastler, Amedeo A. Azizi, Christian Dorfer, Thomas Czech, Christine Haberler, Andreas Peyrl, Rajiv Kumar, Irene Slavc, Sabine Spiegl-Kreinecker, Johannes Gojo, Walter Berger   +19 more
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Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons

Molecular Brain, 2021
Somatostatin-expressing interneurons (SOM-INs) are a major subpopulation of GABAergic cells in CA1 hippocampus that receive excitation from pyramidal cells (PCs), and, in turn, provide feedback inhibition onto PC dendrites.
Anne-Sophie Racine, François-Xavier Michon, Isabel Laplante, Jean-Claude Lacaille   +3 more
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miR-19a/b promote EMT and proliferation in glioma cells via SEPT7-AKT-NF-κB pathway

Molecular Therapy: Oncolytics, 2021
miR-19a/b belong to the miR-17-92 family. We have demonstrated previously that miR-19a/b are overexpressed in glioma and glioma cell lines. However, the role of miR-19a/b in glioma remains unclear.
Weihan Wang, Yubing Hao, Anling Zhang, Weidong Yang, Wei Wei, Guangxiu Wang, Zhifan Jia   +6 more
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Use of a compact high-definition two-dimensional exoscope in surgical treatment of large vestibular schwannoma

Chinese Medical Journal, 2020
. Background:. Extra-corporeal video telescope operating monitor system provides a necessary instrument to perform high-precision neurosurgical procedures that could substitute or supplement the traditional surgical microscope.
Xin Chen, Xiang-Liang Gao, Yan Chai, Ming-Ming Shi, Jian-Ning Zhang, Shu-Yuan Yue, Xiu-Yuan Hao   +6 more
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Inhibition of neutrophil extracellular trap formation attenuates NLRP1-dependent neuronal pyroptosis via STING/IRE1α pathway after traumatic brain injury in mice

Frontiers in Immunology, 2023
IntroductionIncreased neutrophil extracellular trap (NET) formation has been reported to be associated with cerebrovascular dysfunction and neurological deficits in traumatic brain injury (TBI).
Yiyao Cao, Yiyao Cao, Yiyao Cao, Mingming Shi, Mingming Shi, Mingming Shi, Liang Liu, Liang Liu, Liang Liu, Yan Zuo, Haoran Jia, Haoran Jia, Haoran Jia, Xiaobin Min, Xilei Liu, Xilei Liu, Xilei Liu, Zhijuan Chen, Zhijuan Chen, Zhijuan Chen, Yuan Zhou, Yuan Zhou, Yuan Zhou, Shenghui Li, Shenghui Li, Shenghui Li, Guili Yang, Guili Yang, Guili Yang, Xiao Liu, Xiao Liu, Xiao Liu, Quanjun Deng, Quanjun Deng, Quanjun Deng, Fanglian Chen, Fanglian Chen, Xin Chen, Xin Chen, Xin Chen, Shu Zhang, Shu Zhang, Shu Zhang, Jianning Zhang, Jianning Zhang, Jianning Zhang   +45 more
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Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

European Journal of Histochemistry, 2015
Tissue fixation is critical for immunohistochemistry. Recently, we developed a zinc-ethanol-formalin fixative (ZEF), and the present study was aimed to assess the applicability of the ZEF for the human brain histology and immunohistochemistry and to ...
D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev   +3 more
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Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

Frontiers in Immunology, 2021
Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu, Huiming Zhang, Tian-Xiang Zhang, Meng Yuan, Chen Du, Pei Zeng, Zhenning Huang, Dongmei Jia, Guili Yang, Fu-Dong Shi, Fu-Dong Shi, Chao Zhang, Chao Zhang   +12 more
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Central Nervous System Cancers [PDF]

Journal of the National Comprehensive Cancer Network, 2013
Primary and metastatic tumors of the central nervous system are a heterogeneous group of neoplasms with varied outcomes and management strategies. Recently, improved survival observed in 2 randomized clinical trials established combined chemotherapy and radiation as the new standard for treating patients with pure or mixed anaplastic oligodendroglioma ...
Nabors, Louis Burt, Ammirati, Mario, Bierman, Philip J, Brem, Henry, Butowski, Nicholas, Chamberlain, Marc C, DeAngelis, Lisa M, Fenstermaker, Robert A, Friedman, Allan, Gilbert, Mark R, Hesser, Deneen, Holdhoff, Matthias, Junck, Larry, Lawson, Ronald, Loeffler, Jay S, Maor, Moshe H, Moots, Paul L, Morrison, Tara, Mrugala, Maciej M, Newton, Herbert B, Portnow, Jana, Raizer, Jeffrey J, Recht, Lawrence, Shrieve, Dennis C, Sills, Allen K, Tran, David, Tran, Nam, Vrionis, Frank D, Wen, Patrick Y, McMillian, Nicole, Ho, Maria   +30 more
openaire   +4 more sources