Results 21 to 30 of about 24,552,875 (310)

Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

open access: yesEuropean Journal of Histochemistry, 2015
Tissue fixation is critical for immunohistochemistry. Recently, we developed a zinc-ethanol-formalin fixative (ZEF), and the present study was aimed to assess the applicability of the ZEF for the human brain histology and immunohistochemistry and to ...
D.E. Korzhevskii   +3 more
doaj   +1 more source

miR-19a/b promote EMT and proliferation in glioma cells via SEPT7-AKT-NF-κB pathway

open access: yesMolecular Therapy: Oncolytics, 2021
miR-19a/b belong to the miR-17-92 family. We have demonstrated previously that miR-19a/b are overexpressed in glioma and glioma cell lines. However, the role of miR-19a/b in glioma remains unclear.
Weihan Wang   +6 more
doaj   +1 more source

Coronaviruses and the central nervous system [PDF]

open access: yesJournal of NeuroVirology, 2020
Seven coronavirus (CoV) species are known human pathogens: the epidemic viruses SARS-CoV, SARS-CoV-2, and MERS-CoV and those continuously circulating in human populations since initial isolation: HCoV-OC43, HCoV-229E, HCoV-HKU1, and HCoV-NL63. All have associations with human central nervous system (CNS) dysfunction.
openaire   +2 more sources

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 [PDF]

open access: yes
BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19.
GBD 2021 Nervous System Disorders Collaborators   +1 more
core   +3 more sources

Central Nervous System Lipomas.

open access: yesThe Tohoku Journal of Experimental Medicine, 2002
The lipomas of the central nervous system are rare lesions of congenital origin and are located in the medial line and especially in corpus callosum. Intramedullary spinal lipomas can be seen in the life span of 30 years of age and most frequently coincide with initial puberty period. Magnetic resonance imaging and computerized tomography together with
Cirak, B., Kıymaz, Nejmi
openaire   +9 more sources

Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

open access: yesFrontiers in Immunology, 2021
Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu   +12 more
doaj   +1 more source

NLRP1 Inflammasomes: A Potential Target for the Treatment of Several Types of Brain Injury

open access: yesFrontiers in Immunology, 2022
NOD-like receptor (NLR) family pyrin domain-containing 1 (NLRP1) is a member of the NLR family. The NLRP1 inflammasome consists of the NLRP1 protein, the adaptor protein apoptosis-associated speck-like protein containing a CARD domain, and the effector ...
Liang Mi   +8 more
doaj   +1 more source

Epidemiological Analysis of Central Nervous System Teratomas in SEER Database

open access: yes, 2020
Objectives:Teratomas are nongernimmatomatous germ cell tumors of the central nervous system. The aim of this study was to investigate the epidemiological features of central nervous system teratomas.Materials and Methods:Central nervous system teratomas ...
Ercan Bal   +4 more
core   +1 more source

DNA Methylation Associates With Clinical Courses of Atypical Meningiomas: A Matched Case–Control Study

open access: yesFrontiers in Oncology, 2022
BackgroundAccounting for 15–20% of all meningiomas, WHO grade II meningiomas represent an intermediate group regarding risk of tumor recurrence. However, even within this subgroup varying clinical courses are observed with potential occurrence of ...
Matthias Millesi   +21 more
doaj   +1 more source

Targeting sialylation to treat central nervous system diseases. [PDF]

open access: yes, 2021
Sialic acid-binding immunoglobulin-type lectins (SIGLECs) are membrane receptors that are preferentially expressed on immune cells and recognize sialylated proteins, lipids, and RNA.
Neumann, Harald   +5 more
core   +1 more source

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