Results 21 to 30 of about 46,309 (120)

NLRP1 Inflammasomes: A Potential Target for the Treatment of Several Types of Brain Injury

Frontiers in Immunology, 2022
NOD-like receptor (NLR) family pyrin domain-containing 1 (NLRP1) is a member of the NLR family. The NLRP1 inflammasome consists of the NLRP1 protein, the adaptor protein apoptosis-associated speck-like protein containing a CARD domain, and the effector ...
Liang Mi, Liang Mi, Xiaobin Min, Xiaobin Min, Yan Chai, Jianning Zhang, Jianning Zhang, Xin Chen, Xin Chen   +8 more
doaj   +1 more source

Central Nervous System Lipomas.

The Tohoku Journal of Experimental Medicine, 2002
The lipomas of the central nervous system are rare lesions of congenital origin and are located in the medial line and especially in corpus callosum. Intramedullary spinal lipomas can be seen in the life span of 30 years of age and most frequently coincide with initial puberty period. Magnetic resonance imaging and computerized tomography together with
Cirak, B., Kıymaz, Nejmi
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DNA Methylation Associates With Clinical Courses of Atypical Meningiomas: A Matched Case–Control Study

Frontiers in Oncology, 2022
BackgroundAccounting for 15–20% of all meningiomas, WHO grade II meningiomas represent an intermediate group regarding risk of tumor recurrence. However, even within this subgroup varying clinical courses are observed with potential occurrence of ...
Matthias Millesi, Matthias Millesi, Alice Senta Ryba, Alice Senta Ryba, Johannes A. Hainfellner, Johannes A. Hainfellner, Thomas Roetzer, Thomas Roetzer, Anna Sophie Berghoff, Anna Sophie Berghoff, Matthias Preusser, Matthias Preusser, Gerwin Heller, Gerwin Heller, Erwin Tomasich, Erwin Tomasich, Felix Sahm, Felix Sahm, Karl Roessler, Karl Roessler, Stefan Wolfsberger, Stefan Wolfsberger   +21 more
doaj   +1 more source

Endoplasmic Reticulum Stress-Associated Neuronal Death and Innate Immune Response in Neurological Diseases

Frontiers in Immunology, 2022
Neuronal death and inflammatory response are two common pathological hallmarks of acute central nervous system injury and chronic degenerative disorders, both of which are closely related to cognitive and motor dysfunction associated with various ...
Mingming Shi, Mingming Shi, Mingming Shi, Yan Chai, Yan Chai, Jianning Zhang, Jianning Zhang, Jianning Zhang, Xin Chen, Xin Chen, Xin Chen   +10 more
doaj   +1 more source

Tuberculosis of the central nervous system [PDF]

Postgraduate Medical Journal, 1999
Summary Tuberculous involvement of the brain and spinal cord are common neurological disorders in developing countries and have recently shown a resurgence in developed ones. Tuberculous meningitis is an important manifestation and is associated with high morbidity and mortality.
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Women in the field of multiple sclerosis: How they contributed to paradigm shifts

Frontiers in Molecular Neuroscience, 2023
History is full of women who made enormous contributions to science. While there is little to no imbalance at the early career stage, a decreasing proportion of women is found as seniority increases.
Andreia Barateiro, Andreia Barateiro, Catarina Barros, Maria V. Pinto, Ana Rita Ribeiro, Ainhoa Alberro, Ainhoa Alberro, Adelaide Fernandes, Adelaide Fernandes   +8 more
doaj   +1 more source

CENTRAL NERVOUS SYSTEM RESUSCITATION

Emergency Medicine Clinics of North America, 1997
Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities for treatment with novel neuroprotective strategies.
T K, McIntosh, E, Garde, K E, Saatman, D H, Smith   +3 more
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EGFR-vIII downregulated H2AZK4/7AC though the PI3K/AKT-HDAC2 axis to regulate cell cycle progression

Clinical and Translational Medicine, 2020
Background The EGFR-vIII mutation is the most common malignant event in GBM. Epigenetic reprogramming in EGFR-activated GBM has recently been suggested to downregulate the expression of tumour suppressor genes.
Hongyu Zhao, Yunfei Wang, Chao Yang, Junhu Zhou, Lin Wang, Kaikai Yi, Yansheng Li, Qixue wang, Jin Shi, Chunsheng Kang, Liang Zeng   +10 more
doaj   +1 more source

Lipotropin and the Central Nervous System

, 1977
Publisher Summary This chapter deals with the interaction of the lipotropin fragments and related peptides with the central nervous system (CNS). Peptides containing ACTH 4-10, in general, stimulate firing rate, excitability of neurons and neurotransmission, increase cAMP levels, and counteract some morphine-induced CNS effects (inhibition of spinal ...
Gispen, W.H., Ree, J.M. van, Wied, D. de
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Central Nervous System Tuberculosis [PDF]

Baylor University Medical Center Proceedings, 2010
Central nervous system tuberculosis is a rare presentation of active tuberculosis and accounts for about 1% of cases (1). The three clinical categories include meningitis, intracranial tuberculomas, and spinal tuberculous arachnoiditis. We report a case of a young man who presented with active pulmonary tuberculosis in addition to tuberculous ...
Vincent C, Kuo, Louis M, Sloan, Michael, Emmett   +2 more
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