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Medical Clinics of North America, 2020 A head trauma is any injury that results in trauma to the skull, scalp, or brain. Every patient with a suspected head trauma should initially undergo a focused neurological examination which consists of the Glasgow Coma Scale Score (GCS), plus pupillary reactivity, that classifies the traumatic brain injury (TBI) as mild, moderate, or severe.
Mónica Verduzco-Gutierrez
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The synapse in traumatic brain injury [PDF]
Brain, 2020 Traumatic brain injury is a leading cause of death and disability and is a risk factor for dementia later in life. Jamjoom et al. review the role of the synapse in TBI pathophysiology with a focus on the confluence of secondary injury processes including
A. Jamjoom +3 more
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An update on diagnostic and prognostic biomarkers for traumatic brain injury
Expert Review of Molecular Diagnostics, 2018 Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms of TBI.
Yuan Shi, Kevin Wang
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Seminars in Respiratory and Critical Care Medicine, 2002 Traumatic brain injury (TBI) is a serious health issue in the United States, killing 100,000 people a year and serving as a source of long-term disability for many more. It is the leading cause of death in patients under the age of 45 years. Successful management of TBI requires first an appreciation that a significant part of the neuronal injury ...
Kama, Guluma, Brian, Zink
+8 more sources
Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 Abstract There is an increasing incidence of military traumatic brain injury (TBI), and similar injuries are seen in civilians in war zones or terrorist incidents. Indeed, blast-induced mild TBI has been referred to as the signature injury of the conflicts in Iraq and Afghanistan.
Jane E, Risdall, David K, Menon
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Di-san junyi daxue xuebao, 2021 Objective To analyze the influencing factors for tracheostomy decannulation in patients with prolonged disorders of consciousness. Methods Clinical data of 59 cases with prolonged disorders of consciousness and having undergone tracheotomy in Guangdong ...
HE Yanbin +4 more
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Neurology, 2010 In the article “A Prospective Diffusion Tensor Imaging Study in Mild Traumatic Brain Injury” ( Neurology ® 2010;74:643–650), Andrew Mayer and colleagues studied the effects of mild brain injury using a special kind of magnetic resonance image (MRI). The new MRI sequence is called diffusion tensor imaging (DTI).
Emily, Gilmore, Steven, Karceski
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Traumatic brain injuries [PDF]
Nature Reviews Disease Primers, 2016 Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Blennow, K +7 more
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Archives of Physical Medicine and Rehabilitation, 2023 OBJECTIVE To develop new diagnostic criteria for mild traumatic brain injury (TBI) that are appropriate for use across the lifespan and in sports, civilian trauma, and military settings. DESIGN Rapid evidence reviews on 12 clinical questions and Delphi
N. Silverberg +47 more
semanticscholar +1 more source
Scientific Reports, 2022 Traumatic brain injury (TBI) can be associated with long-term neurobehavioral symptoms. Here, we examined levels of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in extracellular vesicles isolated from blood, and their ...
Vivian A. Guedes +16 more
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