Results 41 to 50 of about 46,309 (120)
BackgroundChronic subdural hematoma (CSDH) is common in elderly people with a clear or occult traumatic brain injury history. Surgery is a traditional method to remove the hematomas, but it carries a significant risk of recurrence and poor outcomes.
Ye Tian +40 more
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Tumor immune microenvironment plays an important role in tumorigenesis and metastasis. Polo-like kinases 4 (PLK4) is a crucial regulatory factor in the process of cell cycle, and its abnormal regulation often leads to a variety of diseases including ...
Xiaoyang Zhang +8 more
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Biomaterials for the central nervous system [PDF]
Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural
Yinghui, Zhong, Ravi V, Bellamkonda
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Background Post-traumatic stress disorder (PTSD) is strongly associated with sleep disorders, and current clinical guidelines for PTSD differ in recommending treatment for patients with PTSD associated with sleep disorders.
Yi-Fan Zhao +7 more
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Mitophagy-associated programmed neuronal death and neuroinflammation
Mitochondria are crucial organelles that play a central role in cellular metabolism and programmed cell death in eukaryotic cells. Mitochondrial autophagy (mitophagy) is a selective process where damaged mitochondria are encapsulated and degraded through
Yanlin Zhu +11 more
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BackgroundDelayed hydrocephalus, a severe complication following spontaneous subarachnoid hemorrhage (SAH), lacks reliable early biomarkers. Calcium dysregulation has emerged as a potential mediator of secondary brain injury, but the predictive value of ...
Di Wu +18 more
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Traumatic brain injury (TBI) triggers a robust inflammatory response that is closely linked to worsened clinical outcomes. S100A8/A9, also known as calprotectin or myeloid-related protein-8/14 (MRP8/14), is an alarmin primarily secreted by activated ...
Guihong Shi +16 more
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Actinomycosis of the Central Nervous System :
In 1882 Ponfick1) reported the first case of actinomycosis of the central nervous system. Although more than 100 articles have described actinomycosis of the brain and spinal cord, most cases are insufficiently documented to substantiate the diagnosis2).
H, Ikemoto, N, Hazato, F, Matsumura
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Regeneration in the central nervous system [PDF]
Unlike neonatal axons, mammalian adult axons of the CNS do not regenerate after injury. This developmental loss of regenerative capacity, is correlated with the onset of myelination. Likewise, myelin, or myelin-associated components such as Nogo-A and myelin-associated glycoprotein (MAG) inhibit regeneration from older but not younger neurons ...
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ObjectiveTo elucidate causal roles of circulating immune cells and plasma proteins in diabetic peripheral neuropathy (DPN) pathogenesis using integrative Mendelian randomization (MR) and single-cell validation.MethodsWe employed two-sample MR to assess ...
Chenhao Hu +8 more
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