Results 41 to 50 of about 46,309 (120)

Establishment and validation of a prediction model for self-absorption probability of chronic subdural hematoma

open access: yesFrontiers in Neurology, 2022
BackgroundChronic subdural hematoma (CSDH) is common in elderly people with a clear or occult traumatic brain injury history. Surgery is a traditional method to remove the hematomas, but it carries a significant risk of recurrence and poor outcomes.
Ye Tian   +40 more
doaj   +1 more source

PLK4 initiates crosstalk between cell cycle, cell proliferation and macrophages infiltration in gliomas

open access: yesFrontiers in Oncology, 2022
Tumor immune microenvironment plays an important role in tumorigenesis and metastasis. Polo-like kinases 4 (PLK4) is a crucial regulatory factor in the process of cell cycle, and its abnormal regulation often leads to a variety of diseases including ...
Xiaoyang Zhang   +8 more
doaj   +1 more source

Biomaterials for the central nervous system [PDF]

open access: yesJournal of The Royal Society Interface, 2008
Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural
Yinghui, Zhong, Ravi V, Bellamkonda
openaire   +2 more sources

Psychotherapeutic, pharmacological and other active interventions from the NICE guideline for post-traumatic stress disorder with sleep disorder: systematic review and meta-analysis

open access: yesBMC Psychiatry
Background Post-traumatic stress disorder (PTSD) is strongly associated with sleep disorders, and current clinical guidelines for PTSD differ in recommending treatment for patients with PTSD associated with sleep disorders.
Yi-Fan Zhao   +7 more
doaj   +1 more source

Mitophagy-associated programmed neuronal death and neuroinflammation

open access: yesFrontiers in Immunology
Mitochondria are crucial organelles that play a central role in cellular metabolism and programmed cell death in eukaryotic cells. Mitochondrial autophagy (mitophagy) is a selective process where damaged mitochondria are encapsulated and degraded through
Yanlin Zhu   +11 more
doaj   +1 more source

Serial serum calcium dynamics predict delayed hydrocephalus after spontaneous subarachnoid hemorrhage: development and validation of a clinical nomogram in an observational cohort

open access: yesFrontiers in Neurology
BackgroundDelayed hydrocephalus, a severe complication following spontaneous subarachnoid hemorrhage (SAH), lacks reliable early biomarkers. Calcium dysregulation has emerged as a potential mediator of secondary brain injury, but the predictive value of ...
Di Wu   +18 more
doaj   +1 more source

Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury

open access: yesRedox Biology
Traumatic brain injury (TBI) triggers a robust inflammatory response that is closely linked to worsened clinical outcomes. S100A8/A9, also known as calprotectin or myeloid-related protein-8/14 (MRP8/14), is an alarmin primarily secreted by activated ...
Guihong Shi   +16 more
doaj   +1 more source

Actinomycosis of the Central Nervous System :

open access: yesJapanese Journal of Medical Mycology, 1968
In 1882 Ponfick1) reported the first case of actinomycosis of the central nervous system. Although more than 100 articles have described actinomycosis of the brain and spinal cord, most cases are insufficiently documented to substantiate the diagnosis2).
H, Ikemoto, N, Hazato, F, Matsumura
openaire   +3 more sources

Regeneration in the central nervous system [PDF]

open access: yesExperimental Gerontology, 2003
Unlike neonatal axons, mammalian adult axons of the CNS do not regenerate after injury. This developmental loss of regenerative capacity, is correlated with the onset of myelination. Likewise, myelin, or myelin-associated components such as Nogo-A and myelin-associated glycoprotein (MAG) inhibit regeneration from older but not younger neurons ...
openaire   +2 more sources

Immunoproteomic mediators of diabetic peripheral neuropathy: causal insights from Mendelian randomization and single-cell validation

open access: yesFrontiers in Immunology
ObjectiveTo elucidate causal roles of circulating immune cells and plasma proteins in diabetic peripheral neuropathy (DPN) pathogenesis using integrative Mendelian randomization (MR) and single-cell validation.MethodsWe employed two-sample MR to assess ...
Chenhao Hu   +8 more
doaj   +1 more source

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