Results 41 to 50 of about 70,938 (290)

Case report: Excessive daytime sleepiness as a presenting manifestation of autoimmune glial fibrillary acidic protein astrocytopathy

Frontiers in Immunology, 2023
Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a recently discovered autoimmune inflammatory disease of the central nervous system.
Mingyang Tang, Shuo Huang, Weitong Guo, Junfang Zhou, Zhencan Huang, Wanru Li, Qingqing Sun, Zan Wang   +7 more
doaj   +1 more source

Clinical utility of serum glial fibrillary acidic protein in glial neoplasm

Surgical Neurology International, 2022
Background: Glial fibrillary acidic protein (GFAP) is a member of the cytoskeletal protein family and is widely expressed in astroglial and neural stem cells, also in glial tumors such as astrocytoma and Glioblastoma (GBM). Increased GFAP expression and disruption of the blood–brain barrier are the characteristic features of GBM.
Yadav, Nidhi, Mishra, Keshav, B. C., Anil Kumar, Singh, Daljit, Subberwal, Manju   +4 more
openaire   +2 more sources

Abnormal evoked potentials in autoimmune glial fibrillary acidic protein astrocytopathy

eNeurologicalSci, 2020
Autoimmune GFAP astrocytopathy is a new clinical entity and only a limited number of cases have been reported. Here we report the results of multimodal central conduction studies performed in a case of this disorder.A 72-year-old woman developed gradual ...
Ryo Tokimura, Nozomu Matsuda, Shunsuke Kobayashi, Akio Kimura, Kazuaki Kanai   +4 more
doaj   +1 more source

Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases

, 2013
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Niessner, Marion, Robert Brunkhorst, Brunkhorst, Robert, Helmuth Steinmetz, Steinmetz, Helmuth, Marion Niessner, Mayer, Christoph, Christian Foerch, Pfeilschifter, Waltraud, Christoph A Mayer, Förch, Christian, Waltraud Pfeilschifter   +11 more
core   +1 more source

Glial Fibrillary Acidic Protein as a Biomarker in Acute Ischemic Stroke: Diagnostic Value and Prognostic Implications

Namık Kemal Tıp Dergisi
Stroke is one of the leading causes of mortality and long-term disability worldwide, with ischemic stroke representing the most common subtype. Despite significant progress in neuroimaging and reperfusion therapies, rapid and accurate diagnosis remains a
Ümit ATASEVER
doaj   +1 more source

Autoimmune glial fibrillary acidic protein astrocytopathy

Current Opinion in Neurology, 2019
Purpose of review To describe a recently characterized autoimmune, inflammatory central nervous system (CNS) disorder known as autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy. Recent findings Affected patients present with symptoms of one or more of meningitis ...
Kunchok, Amy, Zekeridou, Anastasia, McKeon, Andrew   +2 more
openaire   +3 more sources

A Case of Adult-Onset Alexander Disease Featuring Severe Atrophy of the Medulla Oblongata and Upper Cervical Cord on Magnetic Resonance Imaging

Case Reports in Neurology, 2012
Adult-onset Alexander disease (AOAD) has been increasingly recognized since the identification of the glial fibrillary acidic protein gene mutation in 2001.
Tadahiro Yonezu, Shoichi Ito, Kazuaki Kanai, Saeko Masuda, Kazumoto Shibuya, Satoshi Kuwabara   +5 more
doaj   +1 more source

Changes in the levels of serum glial fibrillary acidic protein and the correlation with outcomes in severe traumatic brain injury patients

SAGE Open Medicine
Purpose: Glial fibrillary acidic protein serves as a biomarker indicative of astroglial injury, particularly following instances of severe traumatic brain injury.
Kien Trung Nguyen, Tuan Dinh Le, Manh Dang Le, Tien Viet Tran, Cong Van Pham, Ba Van Dang, Son Tien Nguyen, Tam Chi Nguyen, Huy Quang Nguyen, Anh The Vu, Thuc Luong Cong, Hoang Duong Huy, Hai Anh Vu   +12 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy in Pediatric Patients: A Retrospective Study

Frontiers in Pediatrics, 2021
Autoimmune glial fibrillary acidic protein astrocytopathy is a novel form of autoimmune meningoencephalitis related to GFAP autoantibodies. This condition is still being characterized, and few pediatric patients have been identified.
Haixia Huang, Haixia Huang, Ke Bai, Ke Bai, Yueqiang Fu, Yueqiang Fu, Siwei Lu, Siwei Lu, Yunni Ran, Yunni Ran, Hongxing Dang, Hongxing Dang, Jing Li, Jing Li   +13 more
doaj   +1 more source