Results 51 to 60 of about 2,152,561 (262)
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi +4 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
International Journal of Advanced Studies, 2023 Background. The problem of this work is to optimize the currently used methods for calculating the available bandwidth based on analytical calculations by building a simulation model in the AnyLogic software package.
O. D. Pokrovskaya +2 more
doaj +1 more source
Sixth annual Russian Festival of the Educational Bridge Project: Days of Russian Culture at Boston University; Fifty Years After Stalin's Death, The History of Soviet Russia in Sounds [PDF]
, 2003 This is the concert program of the Sixth Annual Russuan Festival of the Educational Bridge Project performance on Sunday, November 16, 2003 at 8:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
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Crystal structure and properties of barium thorate BaThO$_3$ from first principles
, 2013 The phonon spectrum of cubic BaThO$_3$ with the perovskite structure is calculated from first principles within the density functional theory. The analysis of unstable modes in the phonon spectrum enables to determine the symmetry of all possible ...
Lebedev, Alexander I.
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The Educational Bridge Project Fifth Annual Russian Festival: Pushkin's Poetry in Russian Music, October 22, 2002 [PDF]
, 2002 This is the concert program of the Mariinsky Theater Academy of Young Singers performance on Tuesday, October 22, 2002 at 7:00 p.m., at The Castle, 225 Bay State Road.
School of Music, Boston University
core
Cohomological Hall algebra of a symmetric quiver
, 2011 In the paper \cite{KS}, Kontsevich and Soibelman in particular associate to each finite quiver $Q$ with a set of vertices $I$ the so-called Cohomological Hall algebra $\cH,$ which is $\Z_{\geq 0}^I$-graded.
Efimov, Alexander I.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source