Results 31 to 40 of about 7,508 (277)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Assessment of Symptoms Control, Pulmonary Function and Related Quality of Life in Asthmatic Patients Treated with Extrafine Beclomethasone Dipropionate/Formoterol Fumarate 100/6 μg pMDI: Results of a Multicenter Observational Study in Romania (ALFRESCO Study)

open access: yesJournal of Asthma and Allergy, 2022
Ruxandra Ulmeanu,1 Sebastian Bloju,2 Oana Vittos3 1Postgraduate Training School of the Romanian Society of Pulmonology; Bronchoscopy Department - Institute of Pulmonology “Marius Nasta”, Bucharest, Romania; 2Medical Department, Chiesi Romania, Bucharest,
Ulmeanu R, Bloju S, Vittos O
doaj  

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Évaluation de fonctionnalité de traitement des métadonnées par Alfesco en comparaison avec Normetic [PDF]

open access: yes, 2010
Tiré de l'écran-titre (visionné le 27 juin 2017).Cette étude examine les métadonnées repérées par Alfresco dans divers types de documents, afin de voir lesquelles sont ...
Vincent, François
core  

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Reentry and Barriers to Employment: Lessons From Casey's Investments [PDF]

open access: yes, 2016
The job market can be brutal for formerly incarcerated adults, as well as their children and families, as they contend with instability and stress while struggling to secure employment.This report covers the challenging terrains of incarceration, reentry
Bronwyn Mauldin
core  

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Personal archives and Alfresco: representation of information with Dublin Core and folksonomy

open access: closed, 2018
O uso das tecnologias para produção e armazenamento de documentos em todas as áreas da sociedade, tem causado dificuldades no que diz respeito a organização, localização e recuperação de objetos informacionais, que se encontram em diferentes dispositivos e suportes.
Coneglian, Caio Saraiva   +5 more
openaire   +2 more sources

Gestionando los contenidos empresariales con Alfresco

open access: yesTelemática, 2012
El volumen de información no estructurada que se maneja en las organizaciones de hoy es considerable.  La  Gestión  de  Contenidos  Empresariales  (ECM  por  las  siglas  en  inglés  Enterprise  Content  Management)  tiene  como  objetivo  fundamental ...
Laura Roque Córdova
doaj  

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