Results 61 to 70 of about 7,508 (277)
Exploring the Ways Arts and Culture Intersect with Public Safety: Identifying Current Practice and Opportunities for Further Inquiry [PDF]
, 2016 This report describes the range of activities at the intersection of public safety and arts and culture, outlines a theory of change, and provides recommendations for further consideration.
Caroline Ross
core
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Towards a super connected Australia - GenNBN: understanding Australia's most connected generation [PDF]
Foreword Bernard Salt, KPMG partner and social researcher There is one feature that has galvanised Australians across every generation since WWII and possibly longer and that is the irrepressible pursuit of lifestyle.
Bernard Salt
core
Architecting the cyberinfrastructure for National Science Foundation Ocean Observatories Initiative (OOI) [PDF]
, 2016 The NSF Ocean Observatories Initiative (OOI) is a networked ocean research observatory with arrays of instrumented water column moorings and buoys, profilers, gliders and autonomous underwater vehicles (AUV) within different open ocean and coastal ...
Parashar, Manish, Rodero Castro, Iván
core
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Implantación del flujo de trabajo correspondiente al alquiler de transporte terrestre en la empresa de servicios de transporte S.A. (setran S.A), en el segundo semestre 2016 [PDF]
, 2017 Este proyecto de fin de carrera tiene como objetivo diseñar, desarrollar e implantar un flujo de trabajo en una herramienta BPM, y con esto conseguir automatizar, agilizar, centralizar y controlar dicho proceso.
Arostegui García, Carlos José +2 more
core
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
La plataforma iTecSoft: Un caso de colaboración inter-organizativa 2.0. [PDF]
, 2008 El artículo describe la metodología utilizada para abordar el problema de la colaboración intra- e inter-organizativa mediante la descripción del caso específico del proyecto ITECBAN.
Aguirre Herrera, Sandra +10 more
core