Results 61 to 70 of about 200,125 (315)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Evaluating End-User Defensive Approaches Against Phishing Using Education and Simulated Attacks in a Croatian University

open access: yesJournal of Cybersecurity and Privacy
This study investigates the effectiveness of two cybersecurity awareness interventions—phishing simulations and organized online training—in enhancing end-user resilience to phishing attacks in a Croatian university setting.
Zlatan Morić   +3 more
doaj   +1 more source

Branching Densities of Cube-Free and Square-Free Words

open access: yesAlgorithms, 2021
Binary cube-free language and ternary square-free language are two “canonical” representatives of a wide class of languages defined by avoidance properties.
Elena A. Petrova, Arseny M. Shur
doaj   +1 more source

Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method

open access: yesAdvanced Science, EarlyView.
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas   +10 more
wiley   +1 more source

The Safety of Learners and Teachers in School: A Criminological Analysis

open access: yesInternational Journal of Social Sciences & Educational Studies
Recent study revealed that safety of learners and teachers continues to be a matter of major concern in the South African schools. Learners and teachers are no longer safe due to an increased level of violence in the schools.
Puseletso. A Dewee   +2 more
doaj   +1 more source

The composition algebra of a cyclic quiver

open access: yes, 1993
Ringel CM. The composition algebra of a cyclic quiver. Proceedings of the London Mathematical Society : Ser. 3.
Ringel, Claus Michael
core   +1 more source

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

open access: yesAdvanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang   +10 more
wiley   +1 more source

Empirical Performance and Operational Analysis of Monolithic and Distributed Database Architectures in Kubernetes Environments

open access: yesComputers
This study presents a systematic empirical evaluation of monolithic and distributed database architectures deployed in Kubernetes environments. As containerized and cloud-native infrastructures become increasingly prevalent, understanding the performance
Jasmin Redžepagić   +3 more
doaj   +1 more source

A Verified Algebra for Linked Data

open access: yes, 2011
A foundation is investigated for the application of loosely structured data on the Web. This area is often referred to as Linked Data, due to the use of URIs in data to establish links.
Ross Horne   +3 more
core   +1 more source

Ultra‐Wide‐Field Noninvasive Imaging Through Scattering Media Via Physics‐Guided Deep Learning

open access: yesAdvanced Science, EarlyView.
We propose a physics‐guided adaptive dual‐domain learning method for ultra‐wide‐field noninvasive imaging through scattering media, namely UNI‐Net. Our method not only reduces the requirement for real experimental data by an order of magnitude but also enables clear imaging of complex scenes with an ultra‐large field of view, which is 164 times the OME
Lintao Peng   +5 more
wiley   +1 more source

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