Results 51 to 60 of about 13,010 (261)

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

The bulk Hilbert space of double scaled SYK

Journal of High Energy Physics, 2022
The emergence of the bulk Hilbert space is a mysterious concept in holography. In [1], the SYK model was solved in the double scaling limit by summing chord diagrams.
Henry W. Lin
doaj   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

Advanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri, A. Mangiarotti, C. N. Z. Schmitt, R. Dimova   +3 more
wiley   +1 more source

Multiferroic Quantum Criticality in a Proper Ferroelectric Quasi‐one‐dimensional Ising Antiferromagnet

Advanced Science, EarlyView.
Sr1−xBaxCo2V2O8 is established as a magnetic‐ion‐based proper displacive ferroelectric whose transition is continuously suppressed by Ba substitution to a ferroelectric quantum critical point. In the resulting quantum paraelectric regime, a transverse magnetic field induces magnetic quantum criticality, realizing multiferroic quantum criticality and ...
Takayuki Nagai, Peisen Yu, Akitoshi Nakano, Tsuyoshi Kimura   +3 more
wiley   +1 more source

A study of the nonlocal solution of p-Laplacian fractional elliptic problems via approximation methods

Boundary Value Problems
In the present paper, we are concerned with the existence of nonnegative solutions for two Kirchhoff-type problems driven by a fractional p-Laplacian operator, ( − Δ ) p s $(-\Delta )_{p}^{s}$ , in a bounded smooth domain Ω of R N $\mathbb{R}^{N}$ with N
Omar Djidel, Kheireddine Biroud, Med-Salem Rezaoui, Salah Boulaaras, Rafik Guefaifia   +4 more
doaj   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

Advanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau, John J. Foxe, Shlomit Beker, Sophie Molholm   +3 more
wiley   +1 more source

The geometry of Casimir W-algebras

SciPost Physics, 2018
Let $\mathfrak{g}$ be a simply laced Lie algebra, $\widehat{\mathfrak{g}}_1$ the corresponding affine Lie algebra at level one, and $\mathcal{W}(\mathfrak{g})$ the corresponding Casimir W-algebra.
Raphaël Belliard, Bertrand Eynard, Sylvain Ribault
doaj   +1 more source

Updatable Closed‐Form Evaluation of Arbitrarily Complex Multiport Network Connections

Advanced Electronic Materials, EarlyView.
The inverse design of electrically large wave devices often uses reduced‐order multiport models with discrete optimization, requiring many evaluations of complex interconnections between subsystems that differ only in a few blocks. This paper introduces a closed‐form framework enabling efficient Woodbury low‐rank updates of related, previous ...
Hugo Prod'homme, Philipp del Hougne
wiley   +1 more source

Symmetry algebras of stringy cosets

Journal of High Energy Physics, 2019
We find the symmetry algebras of cosets which are generalizations of the minimal-model cosets, of the specific form SU N k × SU N ℓ SU N k + ℓ $$ \frac{\mathrm{SU}{(N)}_k\times \mathrm{SU}{(N)}_{\mathrm{\ell}}}{\mathrm{SU}{(N)}_{k+\mathrm{\ell}}} $$ . We
Dushyant Kumar, Menika Sharma
doaj   +1 more source

Low‐Power Control Of Resistance Switching Transitions in First‐Order Memristors

Advanced Electronic Materials, EarlyView.
Joule losses are a serious concern in modern integrated circuit design. In this regard, minimizing the energy necessary for programming memristors should be handled with care. This manuscript presents an optimal control framework, allowing to derive energy‐efficient programming voltage protocols for resistance switching devices. Following this approach,
Valeriy A. Slipko, Alon Ascoli, Fernando Corinto, Yuriy V. Pershin   +3 more
wiley   +1 more source