Results 141 to 150 of about 2,807 (221)

Quantum algorithms for equational reasoning. [PDF]

open access: yesSci Adv
Rattacaso D   +4 more
europepmc   +1 more source

Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley   +1 more source

Ensemble reliability and the signal‐to‐noise paradox in ECMWF subseasonal forecasts

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
We derive a general expression for the ratio of predictable components (RPC) in terms of correlation, spread–error ratio, and total variance ratio. Physical constraints on the admissible solutions (i.e., real‐valued and non‐negative variances) provide a mechanism to identify statistically paradoxical sample combinations of reliability and correlation ...
Christopher D. Roberts, Frederic Vitart
wiley   +1 more source

New views of some invariants associated with the Cartesian 2D velocity gradient tensor

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Vorticity and divergence of horizontal flow are fundamental quantities in meteorology; both are linear functions of the four elements of the 2D velocity gradient tensor and both are formally unchanged under coordinate rotation. We explore four quadratic functions of the elements that are geometrically invariant in this sense, finding some novel ...
I. Roulstone, S. A. Clough, A. A. White
wiley   +1 more source

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