Results 91 to 100 of about 6,413,659 (289)
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Dynamic and efficient device collaborations in 5G‐advanced and 6G networks
Collaborative transmission, comprising multiple devices owned by a single user, is progressively evolving into an essential strategy to meet the stringent demands of burgeoning collaborative scenarios in 5G‐advanced and 6G networks.
Xianghui Han +5 more
doaj +1 more source
Target Association of Heterogeneous Sensors Based on Nearest-neighbor and Topology
A new data association algorithm is proposed in this paper for heterogeneous sensors information fusion system, which consists of Radar and high-dynamic-range IR, based on joint usage of the nearest-neighbor (NN) and the topology similarity. The proposed
Yuan Ding-bo +3 more
doaj +1 more source
Herman's self-stabilisation algorithm allows a ring of $N$ processors having any odd number of tokens to reach a stable state where exactly one token remains.
Haslegrave, John
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
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David Eppstein, Jean-Claude Falmagne
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Sequential Recommendation Based on Multi-space Attribute Information Fusion [PDF]
The goal of sequential recommendation is to model users' dynamic interests from their historical behaviors,and hence to make recommendations related to the users' interests.Recently,attribute information has been demonstrated to improve the performance ...
WANG Zihong, SHAO Yingxia, HE Jiyuan, LIU Jinbao
doaj +1 more source
Extended Dijkstra algorithm and Moore-Bellman-Ford algorithm
Study the general single-source shortest path problem. Firstly, define a path function on a set of some path with same source on a graph, and develop a kind of general single-source shortest path problem (GSSSP) on the defined path function.
Cheng, Cong-Dian
core
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

