Results 91 to 100 of about 3,365,292 (319)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Target Association of Heterogeneous Sensors Based on Nearest-neighbor and Topology

open access: yesLeida xuebao, 2012
A new data association algorithm is proposed in this paper for heterogeneous sensors information fusion system, which consists of Radar and high-dynamic-range IR, based on joint usage of the nearest-neighbor (NN) and the topology similarity. The proposed
Yuan Ding-bo   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Algorithms for media

open access: yesDiscrete Applied Mathematics, 2008
12 ...
David Eppstein, Jean-Claude Falmagne
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Parametric Polynomial Time Perceptron Rescaling Algorithm [PDF]

open access: yes, 2006
Let us consider a linear feasibility problem with a possibly infinite number of inequality constraints posed in an on-line setting: an algorithm suggests a candidate solution, and the oracle either confirms its feasibility, or outputs a violated ...
Kharechko, Andriy
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Articulation and Clarification of the Dendritic [PDF]

open access: yes, 2008
. The Dendritic Cell algorithm (DCA) is inspired by recent work in innate immunity. In this paper a formal description of the DCA is given. The DCA is described in detail, and its use as an anomaly detector is illustrated within the context of computer ...
Cell Algorithm
core  

In-place Algorithm for Erasing a Connected Component ina Binary Image [PDF]

open access: yes, 2011
Removing noise in a given binary image is a common operation. A generalization of the operation is to erase an arbitrarily specified component by reversing pixel values in the component.
Tetsuo Asano, Asano, Tetsuo
core   +1 more source

Score Images as a Modality: Enhancing Symbolic Music Understanding through Large-Scale Multimodal Pre-Training

open access: yesSensors
Symbolic music understanding is a critical challenge in artificial intelligence. While traditional symbolic music representations like MIDI capture essential musical elements, they often lack the nuanced expression in music scores.
Yang Qin   +5 more
doaj   +1 more source

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