Results 71 to 80 of about 11,719,529 (329)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Dense symmetric temporal alignment learning for human pose estimation [PDF]

open access: yesPeerJ Computer Science
Human pose estimation aims to locate the human joint positions from images or videos. This problem has drawn increasing attention and wide applications in autonomous driving, motion analysis, and intelligence robotics.
Guang Xv, Xingchen Wu
doaj   +2 more sources

Algorithms, Algorithms, Algorithms [PDF]

open access: yesComputer, 2020
James Bret Michael, Jeffrey Voas
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A Knowledge Representation and Reasoning System for Multimodal Neuroimaging Studies

open access: yesInteligencia Artificial, 2017
Multimodal neuroimaging analyses are of major interest for both research and clinical practice, enabling the combined evaluation of the structure and function of the human brain. These analyses generate large volumes of data and consequently increase the
Ana Coelho   +5 more
doaj   +1 more source

A Reduced Latency List Decoding Algorithm for Polar Codes

open access: yes, 2014
Long polar codes can achieve the capacity of arbitrary binary-input discrete memoryless channels under a low complexity successive cancelation (SC) decoding algorithm.
Lin, Jun, Xiong, Chenrong, Yan, Zhiyuan
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Algorithmic polynomials [PDF]

open access: yesProceedings of the 50th Annual ACM SIGACT Symposium on Theory of Computing, 2018
The approximate degree of a Boolean function $f(x_{1},x_{2},\ldots,x_{n})$ is the minimum degree of a real polynomial that approximates $f$ pointwise within $1/3$. Upper bounds on approximate degree have a variety of applications in learning theory, differential privacy, and algorithm design in general.
openaire   +3 more sources

Algorithmic thermodynamics [PDF]

open access: yesMathematical Structures in Computer Science, 2012
Algorithmic entropy can be viewed as a special case of the entropy studied in statistical mechanics. This viewpoint allows us to apply many techniques developed for use in thermodynamics to the subject of algorithmic information theory. In particular, suppose we fix a universal prefix-free Turing machine and letXbe the set of programs that halt for ...
BAEZ, JOHN, STAY, MIKE
openaire   +4 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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