Results 111 to 120 of about 10,989,460 (301)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Algorithmic camouflage: Exploring the shadowbans imposed by algorithms to moderate the content of Chinese gay men

open access: yesBig Data & Society
This study employs semistructured interviews and algorithmic ethnography to explore how algorithmic shadowbans have been used to moderate content related to Chinese gay men and achieve targeted algorithmic governance.
Longxuan Zhao
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Pattern-oriented algorithmic complexity: towards compression-based information retrieval [PDF]

open access: yes, 2010
The assimilation of informational content to computational complexity is more than 50 years old, but a way of exploiting practically this idea came only recently with the definition of compression-based similarity measures, which estimate the amount of ...
Cerra, Daniele
core  

ALGORITHMIC LITERACIES: IDENTIFYING EDUCATIONAL MODELS AND HEURISTICS FOR ENGAGING THE CHALLENGE OF ALGORITHMIC CULTURE

open access: yes, 2023
Algorithms are interwoven in the fabric of digital culture. They increasingly mediate our experience of politics, culture, identity, and agency. Building on critical research in other fields, critical educational theorists are exploring the pervasive ...
Jason Nolan   +5 more
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Boosting popularity: Folk theories and algorithmic resistance of visibility contests in the comment sections

open access: yesBig Data & Society
This study examines the collective actions of Chinese netizens in contesting algorithm visibility through popularity-boosting comments. Employing a netnographic approach within the theoretical frameworks of algorithm resistance and folk theories, the ...
Guoning Zhao
doaj   +1 more source

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