Results 121 to 130 of about 10,989,460 (301)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Formalization: algorithmic approach [PDF]
, 2008 Рассматриваются вопросы формализации задач из различных предметных областей. Предлагается алгоритмический подход к формализации.Questions of formalization of problems from various subject domains are considered.
Провотар, А.И.
core +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
, 2018 A live Algorithmic Poetry performance involving a spontaneously generated script based on Dan Hoeweler’s poem “Computer Virus in My Head”. The performance is influenced and controlled by audience interaction through the use of mobile phones over a local ...
Herbert, D., Hoeweler, D
core
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Causal deconvolution by algorithmic generative models
, 2018 Complex data usually results from the interaction of objects produced by different generating mechanisms. Here we introduce a universal, unsupervised and parameter-free model-oriented approach, based upon the seminal concept of algorithmic probability ...
Zenil, Hector +3 more
core +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Algorithmic Approaches for Inconsistency Measurement [PDF]
Dealing with inconsistent information is an essential task within the field of artificial intelligence. Inconsistency measurement offers a quantitative framework as a means to analyze and interpret such inconsistencies. To be precise, an inconsistency measure computes a numerical value which captures the level of inconsistency.
openaire +2 more sources
, 2019 A live Algorithmic Poetry performance involving a spontaneously generated script based on Dan Hoeweler’s poem “Computer Virus in My Head”. The performance is influenced and controlled by audience interaction through the use of mobile phones over a local ...
Herbert, D., Hoeweler, D
core