Results 61 to 70 of about 386,495 (263)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
An algorithmic approach to Dold-Puppe complexes
, 2009 A Dold-Puppe complex is the image NF\Gamma(C.) of a chain complex C. under the composition of the functors \Gamma, F and N where \Gamma and N are given by the Dold-Kan correspondence and F is a not-necessarily linear functor between two abelian ...
Koeck, Bernhard, Satkurunath, Ramesh
core +2 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
An Algorithmic Approach to Quantum Field Theory
, 2005 The lattice formulation provides a way to regularize, define and compute the Path Integral in a Quantum Field Theory. In this paper we review the theoretical foundations and the most basic algorithms required to implement a typical lattice computation ...
Aoki S. +16 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
THE ALGORITHMIC MODEL OF LABORATORY DIAGNOSTICS OPTIMIZATION
Рациональная фармакотерапия в кардиологии, 2015 The problem of improvement of modern diagnostic technologies is discussed. Introduction of algorithmic approach is able to optimize diagnostics and its costs. Various algorithmic models, their features and structure are reviewed.
G. I. Nazarenko, O. V. Andropova
doaj +3 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Methodological approach to developing algorithmic thinking using educational robots in classroom teaching [PDF]
Методичка праксаAlgorithmic thinking is a problem-solving approach and one of the core skills pupils develop interactively during primary education. One approach to developing algorithmic thinking is working with physical digital devices such as educational robots.
Stoković Gordana T.
doaj +1 more source
Algorithmic Approach to Lower Lid Blepharoplasty [PDF]
Facial Plastic Surgery, 2013 The debate continues around transconjunctival versus transcutaneous approaches. Despite the perceived safety of the former, many experienced surgeons continue to advocate the latter. This review aims to present a balanced view of each approach.
Ryan M, Collar +2 more
openaire +2 more sources
TICAL - a web-tool for multivariate image clustering and data topology preserving visualization [PDF]
, 2011 In life science research bioimaging is often used to study two kinds of features in a sample simultaneously: morphology and co-location of molecular components.
Abouna, Sylvie +5 more
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