Results 71 to 80 of about 392,469 (282)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Аlgorithmic and Conceptual Approach to Figure Surface Measurement
Inovacije u Nastavi, 2019 Surface measurement is an important topic of the school curricula which is closely related to other mathematical topics and to the real world. The results of numerous international studies show that students' achievements in the area of surface ...
Marijana Ž. Zeljić +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Entropy and perpetual computers [PDF]
, 2003 A definition of entropy via the Kolmogorov algorithmic complexity is discussed. As examples, we show how the meanfield theory for the Ising model, and the entropy of a perfect gas can be recovered.
Bhattacharjee, Somendra M.
core +1 more source
An Algorithmic Approach to Chain Recurrence [PDF]
Foundations of Computational Mathematics, 2005 In this paper we give a new definition of the chain recurrent set of a continuous map using finite spatial discretizations. This approach allows for an algorithmic construction of isolating blocks for the components of Morse decompositions which approximate the chain recurrent set arbitrarily closely as well as discrete approximations of Conley's ...
Kalies, W.D. +2 more
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
TICAL - a web-tool for multivariate image clustering and data topology preserving visualization [PDF]
, 2011 In life science research bioimaging is often used to study two kinds of features in a sample simultaneously: morphology and co-location of molecular components.
Abouna, Sylvie +5 more
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
THE ALGORITHMIC MODEL OF LABORATORY DIAGNOSTICS OPTIMIZATION
Рациональная фармакотерапия в кардиологии, 2015 The problem of improvement of modern diagnostic technologies is discussed. Introduction of algorithmic approach is able to optimize diagnostics and its costs. Various algorithmic models, their features and structure are reviewed.
G. I. Nazarenko, O. V. Andropova
doaj +3 more sources