Results 71 to 80 of about 10,989,460 (301)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
An Algorithmic Approach to Perineal Reconstruction
Plastic and Reconstructive Surgery - Global Open, 2019 Summary: Perineal wounds are one of the more challenging plastic surgical defects to reconstruct. Resections in the perineum vary in size and are frequently complicated by radiation, chemotherapy, and contamination. Furthermore, the awkward location and potential need to maintain function of the anus, urethra, and vagina and to
Westbom, Catherine M., Talbot, Simon G.
openaire +2 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Аlgorithmic and Conceptual Approach to Figure Surface Measurement
Inovacije u Nastavi, 2019 Surface measurement is an important topic of the school curricula which is closely related to other mathematical topics and to the real world. The results of numerous international studies show that students' achievements in the area of surface ...
Marijana Ž. Zeljić +1 more
doaj +1 more source
THE DEPRIORITISED APPROACH TO PRIORITISED ALGORITHMS [PDF]
Bulletin of the Australian Mathematical Society, 2009 Abstract
openaire +2 more sources
Algorithmic Information Dynamics
, 2020 Algorithmic Information Dynamics (AID) is an algorithmic probabilistic framework for causal discovery and causal analysis. It enables a numerical solution to inverse problems based or motivated on principles of algorithmic probability.
Abrahão, Felipe +3 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Essays on Algorithmic Trading [PDF]
, 2016 Financial markets and the pace of trading have changed dramatically over the last decade. Stock exchanges have replaced their traditional physical floors with electronic trading platforms.
Osmekhin, Sergey
core
Analysis of binary trading patterns in Xetra [PDF]
, 2010 This paper proposes the Shannon entropy as an appropriate one-dimensional measure of behavioural trading patterns in financial markets. The concept is applied to the illustrative example of algorithmic vs.
Kai-Oliver Maurer +3 more
core +1 more source