Results 91 to 100 of about 282,088 (296)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The “AI Mode”: How Food Delivery Riders in the Netherlands and South Korea Experience Algorithmic Management

Italian Labour Law e-Journal
This study investigates the complex dynamics between algorithmic management and worker agency, focusing on food delivery riders in the Netherlands and South Korea.
Seonok Lee
doaj   +1 more source

Investigation of practical applications of H infinity control theory to the design of control systems for large space structures [PDF]

The applicability of H infinity control theory to the problems of large space structures (LSS) control was investigated. A complete evaluation to any technique as a candidate for large space structure control involves analytical evaluation, algorithmic ...
Irwin, R. Dennis
core   +1 more source

Random matrix over a DVR and LU factorization [PDF]

, 2012
Let R be a discrete valuation ring (DVR) and K be its fraction field. If M is a matrix over R admitting a LU decomposition, it could happen that the entries of the factors L and U do not lie in R, but just in K. Having a good control on the valuations of
Caruso, Xavier
core  

Particle Computation: Complexity, Algorithms, and Logic

, 2017
We investigate algorithmic control of a large swarm of mobile particles (such as robots, sensors, or building material) that move in a 2D workspace using a global input signal (such as gravity or a magnetic field). We show that a maze of obstacles to the
Becker, Aaron T., Demaine, Erik D., Fekete, Sándor P., Lonsforda, Jarrett, Morris-Wright, Rose   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Mapping the research landscape of algorithmic control on workers: A bibliometric analysis

Heliyon
This study provides a comprehensive bibliometric analysis of research on algorithmic control in digital labor platforms, charting the field's intellectual structure and developmental trajectory.
Biqi Li, Yanyuan Cheng
doaj   +1 more source

Integration of symbolic and algorithmic hardware and software for the automation of space station subsystems [PDF]

Traditional expert systems, such as diagnostic and training systems, interact with users only through a keyboard and screen, and are usually symbolic in nature.
Gregg, Hugh, Hack, Edmund, Healey, Kathleen, Wong, Carla   +3 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Multicenter exploration of microbial communities in hospital toilets reveals: antibiotic exposure in nosocomial settings selects for Enterococcus over commensal taxa

Antimicrobial Resistance and Infection Control
Background Excessive antibiotic utilization in hospital settings catalyzes the emergence and dissemination of multidrug resistant (MDR) bacteria, with sanitary facilities serving as critical vectors for their propagation.
Claudio Neidhöfer, Marcel Neuenhoff, Esther Sib, Anna Rehm, Lúcia Ribeiro Dias, Bernd Neumann, Jörg Steinmann, Manuel Döhla, Yousra Kherabi, Ana Budimir, Crystel Hajjar, Rouba Khatib, Katharina Axtmann, Katjana Schwab, Peter Brossart, Steffen Engelhart, Nico T. Mutters, Gabriele Bierbaum, Stefan Janssen, Marijo Parčina   +19 more
doaj   +1 more source