Results 61 to 70 of about 52,658 (295)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Civil society and the (im)possibilities of algorithmic contestation in migration governance
Frontiers in SociologyThe present article examines the (im)possibilities of contesting algorithmic systems in migration governance through an empirical study of civil society organizations in Sweden and Norway.
Stoyanka Andreeva Eneva +2 more
doaj +1 more source
Ethics and discrimination in artificial intelligence-enabled recruitment practices
Humanities & Social Sciences Communications, 2023 This study aims to address the research gap on algorithmic discrimination caused by AI-enabled recruitment and explore technical and managerial solutions. The primary research approach used is a literature review.
Zhisheng Chen
doaj +1 more source
When users control the algorithms: Values expressed in practices on the twitter platform [PDF]
, 2019 Recent interest in ethical AI has brought a slew of values, including fairness, into conversations about technology design. Research in the area of algorithmic fairness tends to be rooted in questions of distribution that can be subject to precise ...
Burrell, J +3 more
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Algorithms and Posthuman Governance [PDF]
Journal of Posthuman Studies, 2017 ABSTRACT Since the Enlightenment, there have been advocates for the rationalizing efficiency of enlightened sovereigns, bureaucrats, and technocrats. Today these enthusiasms are joined by calls for replacing or augmenting government with algorithms and artificial intelligence, a process already substantially under way.
openaire +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
The Triple Ethical Tensions of Intelligent Healthcare
Yixue yu zhexueWhile artificial intelligence (AI) significantly enhances medical efficiency, it also raises a series of ethical concerns, including blurred clinical responsibility, imbalanced data governance, and algorithmic bias.
Yuying HE, Rensheng XIE
doaj +1 more source
Freedom in an Age of Algocracy [PDF]
There is a growing sense of unease around algorithmic modes of governance ('algocracies') and their impact on freedom. Contrary to the emancipatory utopianism of digital enthusiasts, many now fear that the rise of algocracies will undermine our freedom ...
Danaher, John
core
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source