Results 131 to 140 of about 5,009,966 (344)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

The FMB algorithm

open access: yes, 2020
This thesis introduces the FMB algorithm and its C implementation, which can be used to perform intersection detection of pairs of static/dynamic cuboid/tetrahedron in 2D/3D by using the Fourier-Motzkin elimination method. Results show that the FMB algorithm can be in average up to 4.8 times faster than the SAT algorithm.
openaire   +3 more sources

Llamol: a dynamic multi-conditional generative transformer for de novo molecular design

open access: yesJournal of Cheminformatics
Generative models have demonstrated substantial promise in Natural Language Processing (NLP) and have found application in designing molecules, as seen in General Pretrained Transformer (GPT) models.
Niklas Dobberstein   +2 more
doaj   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee   +9 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Evaluating language model embeddings for Parkinson’s disease cohort harmonization using a novel manually curated variable mapping schema

open access: yesScientific Reports
Data Harmonization is an important yet time-consuming process. With the recent popularity of applications using Language Models (LMs) due to their high capabilities in text understanding, we investigated whether LMs could facilitate data harmonization ...
Yasamin Salimi   +5 more
doaj   +1 more source

Log file‐based quality assurance method for respiratory gating system

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background As medical linear accelerator technology advances, enabling higher dose rate deliveries, hypofractionation regimens has increased. This necessitates respiratory gating systems that synchronize radiation delivery with tumor position, requiring simple rigorous quality assurance (QA) to ensure treatment accuracy and patient safety ...
Wonjoong Cheon   +7 more
wiley   +1 more source

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