Results 51 to 60 of about 522,654 (284)

An Efficient Line Search Algorithm for Large Scale Optimization [PDF]

open access: yesAl-Rafidain Journal of Computer Sciences and Mathematics, 2010
In this work we present a new algorithm of gradient descent type, in which the stepsize is computed by means of simple approximation of the Hessian Matrix to solve nonlinear unconstrained optimization function.
Abbas Al-Bayati, Ivan Latif
doaj   +1 more source

From Gap-ETH to FPT-Inapproximability: Clique, Dominating Set, and More

open access: yes, 2017
We consider questions that arise from the intersection between the areas of polynomial-time approximation algorithms, subexponential-time algorithms, and fixed-parameter tractable algorithms.
Chalermsook, Parinya   +6 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Modifications of Flower Pollination, Teacher-Learner and Firefly Algorithms for Solving Multiextremal Optimization Problems

open access: yesAlgorithms, 2022
The article offers a possible treatment for the numerical research of tasks which require searching for an absolute optimum. This approach is established by employing both globalized nature-inspired methods as well as local descent methods for ...
Pavel Sorokovikov, Alexander Gornov
doaj   +1 more source

Handling convexity-like constraints in variational problems

open access: yes, 2014
We provide a general framework to construct finite dimensional approximations of the space of convex functions, which also applies to the space of c-convex functions and to the space of support functions of convex bodies.
Mérigot, Quentin, Oudet, Edouard
core   +4 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Mathematical Modeling on a Physics-Informed Radial Basis Function Network

open access: yesMathematics
The article is devoted to approximate methods for solving differential equations. An approach based on neural networks with radial basis functions is presented. Neural network training algorithms adapted to radial basis function networks are proposed, in
Dmitry Stenkin, Vladimir Gorbachenko
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Exploring Chebyshev polynomial approximations: Error estimates for functions of bounded variation

open access: yesAIMS Mathematics
Approximation theory plays a central role in numerical analysis, evolving through a variety of methodologies, with significant contributions from Lebesgue, Weierstrass, Fourier, and Chebyshev approximations. For sufficiently smooth functions, the partial
S. Akansha, Aditya Subramaniam
doaj   +1 more source

Almost-Smooth Histograms and Sliding-Window Graph Algorithms

open access: yes, 2020
We study algorithms for the sliding-window model, an important variant of the data-stream model, in which the goal is to compute some function of a fixed-length suffix of the stream.
Krauthgamer, Robert, Reitblat, David
core  

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