Results 61 to 70 of about 522,654 (284)
Bicriteria Network Design Problems
, 1997 We study a general class of bicriteria network design problems. A generic problem in this class is as follows: Given an undirected graph and two minimization objectives (under different cost functions), with a budget specified on the first, find a
Hunt III, Harry B. +5 more
core +4 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
A Programmable Look-Up Table-Based Interpolator with Nonuniform Sampling Scheme
International Journal of Reconfigurable Computing, 2012 Interpolation is a useful technique for storage of complex functions on limited memory space: some few sampling values are stored on a memory bank, and the function values in between are calculated by interpolation.
Élvio Carlos Dutra e Silva Júnior +3 more
doaj +1 more source
Nonlinear Analysis, 2022 The proposed multi-objective optimization algorithm hybridizes random global search with a local refinement algorithm. The global search algorithm mimics the Bayesian multi-objective optimization algorithm.
Linas Litvinas
doaj +1 more source
Primal and Dual Approximation Algorithms for Convex Vector Optimization Problems
, 2014 Two approximation algorithms for solving convex vector optimization problems (CVOPs) are provided. Both algorithms solve the CVOP and its geometric dual problem simultaneously. The first algorithm is an extension of Benson's outer approximation algorithm,
Löhne, Andreas +2 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Differentiable Earth mover’s distance for data compression at the high-luminosity LHC
Machine Learning: Science and Technology, 2023 The Earth mover’s distance (EMD) is a useful metric for image recognition and classification, but its usual implementations are not differentiable or too slow to be used as a loss function for training other algorithms via gradient descent. In this paper,
Rohan Shenoy +7 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Failure of the alternating algorithm for best approximation of multivariate functions
Journal of Approximation Theory, 1983 Es seien U und V Teilräume eines normierten Raumes X. Der im Titel erwähnte alternierende Algorithmus führt das Approximationsproblem bzgl. \(U+V\) zurück auf die Approximationsprobleme bzgl. U und V. Die Autoren zitieren Beispiele (aus der Literatur), bei denen der Algorithmus das vorgegebene Approximationsproblem löst und solche, bei denen er es ...
von Golitschek, M, Cheney, E.W
openaire +2 more sources
Communications, 2013 Restoration algorithms of signals and images on the basis of their generalized spectra in bases of orthogonal polynomials and functions at absence and presence of random distortions have been examined. It is shown that in absence of hindrances the number
Oleg V. Chernoyarov +2 more
doaj +1 more source