Results 41 to 50 of about 272,600 (304)

Novel Algorithms for Deductive Games [PDF]

open access: yes, 2011
[[abstract]]This paper presents two novel algorithms for deductive games. First, a k-way-branching algorithm, taking advantage of a clustering technique, is able to efficiently obtain an optimal strategy in the worst case and a near-optimal strategy in ...
Chen, Shan-Tai;Lin, Shun-Shii
core  

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Interfacing Coq + SSReflect with GAP

open access: yes, 2012
Presentation slides and preprint both provided by author. Preprint published in Electronic Notes in Theoretical Computer Science: Proceedings of the 9th International Workshop On User Interfaces for Theorem Provers (UITP10).We report on an extendable ...
Komendantsky, Vladimir   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Information tools for teaching the basics of programming in high school

open access: yesUkrainian Journal of Educational Studies and Information Technology, 2017
The article focuses on the problem of finding methodological approaches to the use of information programming tools in the course of computer science high school. The definition of information tools for teaching as electronic means of storage, processing
Maksym Pavlenko, Tetiana Varava
doaj   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Model Reconstruction from Small-Angle X-Ray Scattering Data Using Deep Learning Methods

open access: yesiScience, 2020
Summary: Small-angle X-ray scattering (SAXS) method is widely used in investigating protein structures in solution, but high-quality 3D model reconstructions are challenging.
Hao He, Can Liu, Haiguang Liu
doaj   +1 more source

A Computer Science Perspective on the Bendsimplification Algorithm

open access: yesCartography and Geographic Information Science, 1999
The primary aim of this study was to evaluate whether the use of bends provides a better basis than point elimination for research on line structuring. These investigations were undertaken using Arc/Info 7.1.1. Comparative experimental results suggest that the algorithm may not be as widely applicable as the much simpler geometric filters, such as the ...
Visvalingam, M., Herbert, S.
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Second derivative two-step peer methods

open access: yesMathematical Modelling and Analysis
This paper is devoted to extending two-step peer methods, for the numerical solution of ordinary differential equations, for the case where the second derivative of the solution is incorporated into the formula of the methods.
Mohammad Sharifi   +3 more
doaj   +1 more source

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