Results 241 to 250 of about 4,210,741 (299)
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu +12 more
wiley +1 more source
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma +14 more
wiley +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal +25 more
wiley +1 more source
New alien species and alien species of rare occurrence in the flora of Khabarovsky Krai
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Alien Species in European Waters
2002In this paper we review from a historical perspective some of the human activities that have facilitated the potential of alien species from all continents but Antarctica to become established in coastal and inland waters of Europe.
Leppäkoski, Erkki +2 more
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Alien Species of Fish Helminths of Belarus
Russian Journal of Biological Invasions, 2021The article provides data on the species composition of alien helminth species, which infest introduced fish species in pond fish farms, and also the literature data on natural reservoirs of Belarus. Seven alien helminth species have been revealed in introduced fish in reservoirs of Belarus ( Khawia sinensis Hsü, 1935, Schyzocotyle acheilognathi ...
Е. I. Bychkova +2 more
openaire +1 more source
2019
This chapter studies the causes and consequences of invasive alien species (IAS), as well as the methods to manage and mitigate their impacts. A native species (or indigenous species) is one that occurs within its natural range (past or present) and that does so in the absence of dispersal that is assisted, either directly or indirectly, by humans.
Bradley J. Cardinale +2 more
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This chapter studies the causes and consequences of invasive alien species (IAS), as well as the methods to manage and mitigate their impacts. A native species (or indigenous species) is one that occurs within its natural range (past or present) and that does so in the absence of dispersal that is assisted, either directly or indirectly, by humans.
Bradley J. Cardinale +2 more
openaire +1 more source
2020
(Uploaded by Plazi for the IPBES Invasive Alien Species Assessment) No abstract provided.
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(Uploaded by Plazi for the IPBES Invasive Alien Species Assessment) No abstract provided.
openaire +2 more sources

