Results 101 to 110 of about 1,546,431 (297)
HMM word-to-phrase alignment with dependency constraints [PDF]
, 2010 In this paper, we extend the HMMwordto-phrase alignment model with syntactic dependency constraints. The syntactic dependencies between multiple words in one language are introduced into the model in a bid to produce coherent alignments.
Way, Andy, Ma, Yanjun
core +3 more sources
Model Recalibration for Regional Bias Reduction in Dynamic Microsimulations
MathematicsDynamic microsimulations are tools to stochastically project (synthetic) microdata into the future. In spatial microsimulations, regional discrepancies are of particular interest and must be considered accordingly.
Jan Weymeirsch +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Integrated multiple sequence alignment [PDF]
, 2005 Sammeth M. Integrated multiple sequence alignment. Bielefeld (Germany): Bielefeld University; 2005.The thesis presents enhancements for automated and manual multiple sequence alignment: existing alignment algorithms are made more easily accessible and ...
Sammeth, Michael
core
Alignment of IT projects with business strategy: An analysis of the interrelationships between the factors affecting IS alignment at strategic, tactical and operational levels [PDF]
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Despite numerous efforts to integrate business and IS strategic plans, organisations are not delivering the expected benefits from IS investment.
Gutiérrez Mendoza, Anabel Sara
core +3 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2019 This study carried out a theoretical examination of the method of preparing very long unidirectional CNTs/resin composites by the application of an electric field.
Hiroshi SUZUKI
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source