Results 71 to 80 of about 1,546,431 (297)

LEADERSHIP AND STRATEGIC ALIGNMENT IN CONSTRUCTION [PDF]

open access: yes, 2010
Construction management and engineering is generally thought of as a purely technical part of construction management consisting of bar charts, scheduling, estimates and bidding. While these tools may guide a company to construct a project, the
Acacio, PhD, Alexis A.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

To Align or Not to Align: Strategic Multimodal Representation Alignment for Optimal Performance

open access: yesProceedings of the AAAI Conference on Artificial Intelligence
Multimodal learning often relies on aligning representations across modalities to enable effective information integration—an approach traditionally assumed to be universally beneficial. However, prior research has primarily taken an observational approach, examining naturally occurring alignment in multimodal data and exploring its correlation with ...
Wanlong Fang, Tianle Zhang, Alvin Chan
openaire   +3 more sources

Global Network Alignment [PDF]

open access: yes, 2010
Motivation: High-throughput methods for detecting molecular interactions have lead to a plethora of biological network data with much more yet to come, stimulating the development of techniques for biological network alignment.
Oleksii Kuchaiev, Natasa Przulj
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Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

To Align or Not to Align? That Is the Question

open access: yesJournal of Geophysical Research: Atmospheres
Abstract Previous studies have shown that vertically misaligned circulations are commonly found in weaker tropical cyclones (TCs) below hurricane strength, whereas TCs of hurricane intensity more typically exhibit vertically aligned vortices.
Michael S. Fischer   +3 more
openaire   +1 more source

A Robust Linear Feature-Based Procedure for Automated Registration of Point Clouds

open access: yesSensors, 2015
With the variety of measurement techniques available on the market today, fusing multi-source complementary information into one dataset is a matter of great interest. Target-based, point-based and feature-based methods are some of the approaches used to
Martyna Poreba, François Goulette
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Report to the Governor from the Mental Health Alignment Workgroup

open access: yes, 2001
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.At head of title: State of Oregon"January 2001."Includes ...

core  

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