Results 91 to 100 of about 2,590,839 (306)

Optimal Image Alignment With Random Measurements

, 2009
Publication in the conference proceedings of EUSIPCO, Glasgow, Scotland ...
Kokiopoulou, Effrosyni, Kressner, Daniel, Frossard, Pascal   +2 more
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Alignment optimization.

, 2021
Interaction maps for deletion sites identified from the deletion dataset of synthetic reads for BWA-MEM alignment with (A) default parameters and (B) optimized algorithm.
Thomas W. Christy (11836547), Alain Laederach (243452), Kevin M. Weeks (367405), Catherine A. Giannetti (10967274)   +3 more
core   +1 more source

Human-in-the-Loop Optimization of the Stiffness and Alignment of a Prosthetic Foot to Reduce the Metabolic Cost of Walking

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Improper tuning of prosthetic foot properties to the individual user limits the efficacy of current state-of-the-art prosthetic feet in terms of walking economy.
Thijs Tankink, Han Houdijk, Johnnidel Tabucol, Marco Leopaldi, Juha M. Hijmans, Raffaella Carloni   +5 more
doaj   +1 more source

School and Teacher Information, Communication and Technology (ICT) readiness across 57 countries: The alignment optimization method. [PDF]

Educ Inf Technol (Dordr), 2023
Wu R, Yang W, Rifenbark G, Wu Q.
europepmc   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Horizontal alignment optimization in road design

, 2014
The horizontal alignment optimization problem in road design is a complex problem. Usually, classic optimization techniques cannot be used to address the problem. A few studies investigated the problem mainly using heuristics.
Mondal, Sukanto
core   +1 more source

Capture the high-efficiency non-fullerene ternary organic solar cells formula by machine-learning-assisted energy-level alignment optimization. [PDF]

Patterns (N Y), 2021
Hao T, Leng S, Yang Y, Zhong W, Zhang M, Zhu L, Song J, Xu J, Zhou G, Zou Y, Zhang Y, Liu F.   +11 more
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source