Results 131 to 140 of about 2,590,839 (306)

Digital-twin driven alignment control method for marine shafting with air spring vibration isolation system

open access: yesScientific Reports
Shafting alignment is crucial for marine propulsion systems and may affect the safety and stability of ship operations. Air spring vibration isolation systems (ASVISs) for marine shafting can help control the shafting alignment state by actively ...
Song Liu, Liang Shi, Wei Xu, ZeChao Hu
doaj   +1 more source

Automatic Texture Alignment by Optimization Method

open access: yesMicroscopy and Microanalysis
Abstract Microstructure analysis via electron backscatter diffraction has become an indispensable tool in materials science and engineering. In order to interpret or predict the anisotropy in crystalline materials, the texture is assessed, e.g. via pole figure diagrams.
Alois C Ott   +4 more
openaire   +2 more sources

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Optimization of the Next-Generation Sequencing Data Alignment

open access: yes, 2014
This thesis presents short DNA alignment tools optimization. These short DNA reads are products of next\nobreakdash-generation sequencing technologies. The results produced by existing align\-ment tools can be influenced by various parameters.
Šalanda, Vojtěch
core   +1 more source

HC-SPA: Hyperbolic Cosine-Based Symplectic Phase Alignment for Fusion Optimization

open access: yesSensors
In multimodal collaborative learning, the gradient dynamics of heterogeneous modalities face significant challenges due to the curvature heterogeneity of parameter manifolds and mismatches in phase evolution.
Wenlong Zhang   +3 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

open access: yesFEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi   +6 more
wiley   +1 more source

Optimizing Sequence Alignment with Scored NFAs

open access: yesCoRR
The rapid increase in symbolic data has underscored the significance of pattern matching and regular expression processing. While nondeterministic finite automata (NFA) are commonly used for these tasks, they are limited to detecting matches without determining the optimal one.
Ryan Karbowniczak, Rasha Karakchi
openaire   +2 more sources

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Study on Calculation Method for Incremental Launching Based on Nonlinear Analysis

open access: yesZhongwai Gonglu
In view of the shortcomings of traditional incremental launching calculation methods and the assembly construction control of incremental launching beams, an incremental launching calculation method based on nonlinear analysis was proposed in this paper.
MO Shanfeng, HUANG Cailiang, QIN Hui
doaj   +1 more source

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