Results 51 to 60 of about 2,590,839 (306)

An Optimized System for Multiple Sequence Alignment

open access: yes2009 International Conference on Reconfigurable Computing and FPGAs, 2009
Multiple sequence alignment (MSA) is one of the essential operations for identifying functional and structural relations among proteins. The execution of an MSA algorithm requires high-performance platforms. This paper presents a hardware system that speeds up the popular MSA software ClustalW.
Çaglar Yilmaz, Mustafa Gök
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Multiple sequence alignment with the Divide-and-Conquer method. [PDF]

open access: yes, 1998
Stoye J. Multiple sequence alignment with the Divide-and-Conquer method. Gene. 1998;211(2):GC45-GC56.An improved algorithm for the simultaneous alignment of multiple protein and nucleic acid sequences, the Divide-and-Conquer Alignment procedure (DCA), is
Jens Stoye   +1 more
core   +1 more source

Image Redundancy Filtering for Panorama Stitching

open access: yesIEEE Access, 2020
In this paper, we designed a novel framework for massive image panorama stitching, which aims to resolve image redundancy, alignment error accumulation and perspective distortion accumulation of the stitching process.
Xin Wei   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Interference alignment at intermediate SNR with perfect or noisy CSI [PDF]

open access: yes, 2010
Interference alignment is a new technique combining transmitter precoding and receiver interference suppression to achieve the optimal multiplexing gain in interference networks by exploiting knowledge of channel state information of all transmission ...
Miatton , Federico
core  

Sequence alignment, mutual information, and dissimilarity measures for constructing phylogenies [PDF]

open access: yes, 2011
Background: Existing sequence alignment algorithms use heuristic scoring schemes based on biological expertise, which cannot be used as objective distance metrics.
Penner, Orion   +8 more
core   +2 more sources

A Survey of Nature-Inspired Meta-Heuristic Algorithms in Network Alignment [PDF]

open access: yesAdvances in Engineering and Intelligence Systems
Network alignment plays a pivotal role in fields such as network science, biology, and social network analysis by identifying common structures and relationships across different networks.
Anagh Awal, Farsuram Pandit
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Least squares contour alignment

open access: yes, 2009
The contour alignment problem, considered in this paper, is to compute the minimal distance in a least squares sense, between two explicitly represented contours, specified by corresponding points, after arbitrary rotation, scaling, and translation of ...
Markovsky, Ivan, Mahmoodi, Sasan
core   +1 more source

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