Amidochromenes for Promising Antileishmanial Activity
Natural Product Communications, 2017 Numerous natural products having a 2,2-dimethylchromene (2,2-dimethylbenzopyrane) structural element present interesting biological activities that may, therefore, be considered as privileged pharmacophore.
Abdelhak Neghra +5 more
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An unprecedented palladium-arsenic catalytic cycle for nitriles hydration
Frontiers in Chemistry, 2023 An unprecedented palladium/arsenic-based catalytic cycle for the hydration of nitriles to the corresponding amides is here described. It occurs in exceptionally mild conditions such as neutral pH and moderate temperature (60°C).
Damiano Cirri +2 more
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Synthesis of methylenebisamides using CC- or DCMT-activated DMSO
Beilstein Journal of Organic Chemistry, 2008 Bisamides are key fragments for the introduction of gem-diaminoalkyl residues into retroinverso pseudopeptide derivatives and in the synthesis of peptidomimetic compounds. The literature methods for these types of compounds have certain drawbacks.
Qiang Wang +3 more
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NaY Zeolite: A Useful Catalyst for Nitrile Hydrolysis
Molecules, 2000 The NaY zeolite catalysed hydrolysis of nitriles to primary amides is reported. It is found that aryl nitriles with strong electron-withdrawing substituents and cyanopyridines are readily hydrolysed in the water suspension, while aliphatic nitriles do ...
Bogdan A. Ã…Â olaja +3 more
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Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp3)−H Bonds [PDF]
, 2015 The transition-metal-catalyzed direct C–H bond fluorination is an attractive synthetic tool toward the preparation of organofluorines. While many methods exist for the direct sp3 C–H functionalization, site-selective fluorination of unactivated sp3 ...
Ge, Haibo +3 more
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Elastic modulus in the crystalline region of poly(p-phenylene terephthalamide) [PDF]
, 1976 Fibres from aromatic polyamides have a much higher Young's modulus than fibres from aliphatic polyamides. In order to contribute to the explanation of this observed difference we looked at one of the ultimate properties, the elastic modulus in the ...
Bantjes, A. +3 more
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An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]
, 2018 Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
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A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis. [PDF]
, 2016 A long-standing challenge in synthetic chemistry is the development of the transamidation reaction. This process, which involves the conversion of one amide to another, is typically plagued by unfavourable kinetic and thermodynamic factors. Although some
Anthony, Sarah M +4 more
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Synthesis, Docking Studies and Acetylcholinesterase Inhibition of Open-Chain Carbohydrate Amides
Medical Sciences Forum, 2022 Alzheimer’s disease (AD) is the most common age-related cause of dementia among elderly people. AD is a severe neurodegenerative disorder characterized by progressive memory and cognition loss that leads to disability and inevitably to death and is ...
Maria Isabel Ismael +6 more
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Three-electron two-centred bonds and the stabilisation of cationic sulfur radicals [PDF]
, 2014 Electronic communication in biological systems is fundamental to understanding protein signalling and electron hopping pathways. Frequently studied examples are cationic radical methionine and its functional derivatives.
Carbery, DR, Hendon, CH, Walsh, A
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