Results 21 to 30 of about 14,155 (281)

Copper/N,N-Dimethylglycine Catalyzed Goldberg Reactions Between Aryl Bromides and Amides, Aryl Iodides and Secondary Acyclic Amides

open access: yesMolecules, 2014
An efficient and general copper-catalyzed Goldberg reaction at 90–110 °C between aryl bromides and amides providing the desired products in good to excellent yields has been developed using N,N-dimethylglycine as the ligand.
Liqin Jiang
doaj   +1 more source

Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): Allylbenzenes have been recently developed as inhibitors of lipoxygenases. They decrease peroxidation activity via mimicking 1,4-unsaturated bonds of fatty acids by their allyl portion.
Mina Mousavian   +5 more
doaj   +1 more source

Chemoselective α‑Sulfidation of Amides Using Sulfoxide Reagents [PDF]

open access: yes, 2020
The direct α-sulfidation of tertiary amides using sulfoxide reagents under electrophilic amide activation conditions is described. Employing convenient and readily available reagents, selective functionalization takes place to generate isolable sulfonium
Movassaghi, Mohammad   +5 more
core   +1 more source

Catalytic enantioselective reductive alkynylation of amides enables one-pot syntheses of pyrrolidine, piperidine and indolizidine alkaloids

open access: yesNature Communications, 2023
The primary objective in synthetic organic chemistry is to develop highly efficient, selective, and versatile synthetic methodologies, which are essential for discovering new drug candidates and agrochemicals. In this study, we present a unified strategy
Fang-Fang Xu   +3 more
doaj   +1 more source

An efficient method for the construction of polysubstituted 4-pyridones via self-condensation of β-keto amides mediated by P2O5 and catalyzed by zinc bromide

open access: yesBeilstein Journal of Organic Chemistry, 2013
A self-condensation cyclization reaction mediated by phosphorus pentoxide (P2O5) and catalyzed by zinc bromide (ZnBr2) is presented for the synthesis of polysubstituted 4-pyridones and 2-pyridones from β-keto amides.
Liquan Tan   +3 more
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 94, Revision 2 (FGE.94Rev2): Consideration of aliphatic amines and amides evaluated in an addendum to the group of aliphatic and aromatic amines and amides evaluated by the JECFA (68th meeting) [PDF]

open access: yesEFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Amidochromenes for Promising Antileishmanial Activity

open access: yesNatural Product Communications, 2017
Numerous natural products having a 2,2-dimethylchromene (2,2-dimethylbenzopyrane) structural element present interesting biological activities that may, therefore, be considered as privileged pharmacophore.
Abdelhak Neghra   +5 more
doaj   +1 more source

An unprecedented palladium-arsenic catalytic cycle for nitriles hydration

open access: yesFrontiers in Chemistry, 2023
An unprecedented palladium/arsenic-based catalytic cycle for the hydration of nitriles to the corresponding amides is here described. It occurs in exceptionally mild conditions such as neutral pH and moderate temperature (60°C).
Damiano Cirri   +2 more
doaj   +1 more source

Ligand-Enabled Pd(II)-Catalyzed Enantioselective β-C(sp3)-H Arylation of Aliphatic Tertiary Amides

open access: yes, 2022
Amide is one of the most widespread functional groups in organic and bioorganic chemistry, and it would be valuable to achieve stereoselective C(sp3)-H functionalization in amide molecules. Pd(II) catalysis has been prevalently used in the C-H activation
Lei, Jiao   +2 more
core   +1 more source

Synthesis of methylenebisamides using CC- or DCMT-activated DMSO

open access: yesBeilstein Journal of Organic Chemistry, 2008
Bisamides are key fragments for the introduction of gem-diaminoalkyl residues into retroinverso pseudopeptide derivatives and in the synthesis of peptidomimetic compounds. The literature methods for these types of compounds have certain drawbacks.
Qiang Wang   +3 more
doaj   +1 more source

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