Results 151 to 160 of about 35,022 (246)

IL‐6 Upregulates CD73 in Human Placental Mesenchymal Stem Cells to Promote ATRA‐Induced NB4 Cell Differentiation in Acute Promyelocytic Leukemia

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Purpose To investigate the expression profile of IL‐6 in patients with acute promyelocytic leukemia (APL) and its role in modulating the ability of hPMSCs to regulate the differentiation of NB4 cells. Methods Peripheral blood samples were obtained from newly diagnosed APL patients and healthy controls.
Rong Qi, Hengchao Zhang, Yunhua Wu, Yanchao Ma, Xiying Luan   +4 more
wiley   +1 more source

Hyaluronan Regulates Vascular Smooth Muscle Cell Osteogenic Differentiation and Vascular Calcification. [PDF]

Biomolecules
Roy S, Kane J, Grigorieva I, Roche-Dugmore D, Moore S, Steadman R, Raby AC, Jakulj L, Schurgers L, Lutgens E, Eringa EC, Vervloet M, Fraser D, Meran S.   +13 more
europepmc   +1 more source

hUC‐MSCs via β‐NGF Alleviate Cognitive Impairment After Tibial Fracture Surgery by Regulating the STMN2/NMNAT2‐SARM1‐NF‐κB Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This study found that human umbilical cord mesenchymal stem cells secrete β‐NGF, which binds to the TrkA receptor on neurons, upregulates the protein levels of STMN2 and NMNAT2 in mice with perioperative neurocognitive disorders, and thereby downregulates the protein levels of SARM1 and p‐NF‐κB.
Kai Wang, Fangjun Wang, Yuhan Zhang, Wenbo Li, Shuai Li, Ying Zhou, Guangkuo Ma, Ziwei Xia, Xueyan Zhou, Liwei Wang   +9 more
wiley   +1 more source

Involvement of AKT/β-catenin in Enhanced Osteogenesis by Cannabidiol in Bone Stromal Cells Harvested from Human Tori. [PDF]

Sci Rep
Makeudom A, Taechukorn M, Muenhong K, Danvirunhavanit P, Petchnuan J, Dechtham E, Sangkaew P, Suamphan S, Krisanaprakornkit S.   +8 more
europepmc   +1 more source

Osteoimmunomodulatory Effects of Zirconia‐Modified Titanium: Promoting Macrophage Activation and Osteoblast Mineralization at the Dental Implant Interface

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objective Immune cells are the first to interact with implant surfaces, yet their contribution to osseointegration is often underestimated. Understanding how titanium‐based and zirconia‐enriched surface properties regulate macrophage polarization is essential for designing regenerative biomaterials.
Ottavia Cannatella, Biagio Matera, Francesca Rossi, Giovanni Passeri, Simone Lumetti, Ludovica Parisi, Benedetta Ghezzi   +6 more
wiley   +1 more source

Histological concordance of medial arterial calcification between tibial and peroneal arteries in advanced peripheral arterial disease. [PDF]

JVS Vasc Sci
Adler S, RuizdelRio J, Eliceiri B, Gaffey AC.   +3 more
europepmc   +1 more source

Effect of Osteoblast‐Extracellular Matrix‐Functionalized Nanostructured Titanium Surface on Osteoblastic Cell Behavior

Journal of Biomedical Materials Research Part A, Volume 114, Issue 8, August 2026.
ABSTRACT Nanostructured titanium (Ti) facilitates osteoblast differentiation by modulating various signaling pathways and may enhance osseointegration, potentially through its influence on the formation and remodeling of the extracellular matrix (ECM). This study aimed to investigate the impact of osteoblast‐ECM‐functionalized nanostructured Ti surface
Georgia Kors Quiles, Paola Gomes Souza, Maria Paula Oliveira Gomes, Rayana Longo Bighetti‐Trevisan, Leticia Faustino Adolpho, Helena Bacha Lopes, Adalberto Luiz Rosa, Marcio Mateus Beloti   +7 more
wiley   +1 more source

Optimizing graphene-enhanced polycaprolactone scaffolds for bone tissue engineering. [PDF]

J Oral Biol Craniofac Res
Anitasari S, Tandirogang N, Irawiraman H, Budi HS, Shen YK, Alus LN, Nuraini P.   +6 more
europepmc   +1 more source

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu, Yi‐Fan Gu, Jian‐Qiao Li, Yi‐Heng Li, Yu‐Hu Chen, Lin‐Hui Wang, Zi‐Ru Wang, Yi‐Cong Wang, Min Yang   +8 more
wiley   +1 more source

ZIF-8-coated 3D-printed PCL/ion-doped BCP scaffolds for enhanced bone regeneration. [PDF]

PLoS One
Ardakani VK, Boroumand N, Dini G, Golabi M, Asl MA.   +4 more
europepmc   +1 more source