Results 1 to 10 of about 1,038 (169)

The Effective Treatment of Purpurin on Inflammation and Adjuvant-Induced Arthritis [PDF]

Molecules, 2023
Rubia cordifolia L. (Rubiaceae), one of the traditional anti-rheumatic herbal medicines in China, has been used to treat rheumatoid arthritis (RA) since ancient times.
Ping Yan, Shen Caihong
exaly   +6 more sources

On the Role of ROS and Glutathione in the Mode of Action Underlying Nrf2 Activation by the Hydroxyanthraquinone Purpurin [PDF]

Antioxidants, 2023
Purpurin is a major anthraquinone present in the roots of Rubia cordifolia (madder). Purpurin is known to activate Nrf2 (Nuclear transcription factor erythroid 2-related factor 2) EpRE (electrophile responsive element) mediated gene expression as a ...
Qiuhui Ren, Wouter Bakker, Sebastiaan Wesseling, Hans Bouwmeester, Ivonne M. C. M. Rietjens   +4 more
doaj   +2 more sources

Purpurin suppresses atopic dermatitis via TNF-α/IFN-γ-induced inflammation in HaCaT cells

International Journal of Immunopathology and Pharmacology, 2022
Objective We investigated whether purpurin inhibits various pathways of inflammation leading to atopic dermatitis. Introduction 1,2,4-Trihydroxyanthraquinone, commonly called purpurin, is an anthraquinone that is a naturally occurring red/yellow dye ...
Sang-Bae Han, Ok-Kyoung Kwon, Kyung-Seop Ahn   +2 more
exaly   +2 more sources

Purpurin Rescues Contrast-Induced Acute Rat Kidney Injury via Inducing Autophagy and Inhibiting Apoptosis [PDF]

Pharmaceuticals
Objectives: Contrast-induced acute kidney injury (CIAKI) is a major cause of hospital-acquired renal injury, and strategies for its treatment are currently lacking.
Kangxu He, Xiaoying Sun, Xinhui Pan, Xiaoda Yang, Qi Wang, Kai Liao   +5 more
doaj   +2 more sources

Copper-mediated DNA damage caused by purpurin, a natural anthraquinone [PDF]

Genes and Environment, 2022
Background Purpurin (1,2,4-trihydroxy-9,10-anthraquinone), a natural red anthraquinone pigment, has historically been used as a textile dye. However, purpurin induced urinary bladder tumors in rats, and displayed a mutagenic activity in assay using ...
Hatasu Kobayashi, Yurie Mori, Ryo Iwasa, Yuichiro Hirao, Shinya Kato, Shosuke Kawanishi, Mariko Murata, Shinji Oikawa   +7 more
doaj   +2 more sources

Structural and functional insights into the selective inhibition of mutant tau aggregation by purpurin and oleocanthal in frontotemporal dementia. [PDF]

Protein Sci
Abstract Tau aggregation driven by microtubule‐associated protein tau (MAPT) mutations is central to frontotemporal dementia pathology, yet no disease‐modifying therapies effectively target mutant tau. Here, we identify purpurin (PUR) and oleocanthal (OLC) as selective inhibitors of mutant tau aggregation using peptide models spanning the R2R3 ...
Goud AC, Kozlov I, Skoupilová P, Malina L, Roy S, Das V.   +5 more
europepmc   +2 more sources

Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview [PDF]

Metabolites, 2022
The Rubia genus includes major groups of medicinal plants such as Rubia cordifolia, Rubia tinctorum, and Rubia akane. They contain anthraquinones (AQs), particularly alizarin and purpurin, which have pharmacological effects that are anti-inflammatory ...
Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Kee Yoeup Paek, So Young Park   +3 more
doaj   +2 more sources

Multianalytical Study of Amuletic and Talismanic Islamic-African Paper Manuscripts in the Slovene Ethnographic Museum. [PDF]

Chempluschem
The image illustrates a multi‐technique analysis of Islamic‐African manuscripts from the nineteenth to twentieth centuries. It highlights methods like microscopy, hyperspectral imaging, FTIR, LIF, Raman, LIBS, and furnish analysis used to study paper fibers, inks, and dyes—revealing a blend of local and trade materials and a rich fusion of Qur’anic and
Elnaggar A, Mahgoub H, Maestro-Guijarro L, Crespo Ibáñez A, María Carmona-Quiroga P, Sánchez-Cortés S, Rehar Ž, Kos G, Ameen A, Frelih M, Strlič M, Oujja M, Castillejo M.   +12 more
europepmc   +2 more sources

Effects of geographical, soil and climatic factors on the two marker secondary metabolites contents in the roots of Rubia cordifolia L. [PDF]

Frontiers in Plant Science
The growth and quality of medicinal plants depend heavily on environmental variables. The quality of Rubia cordifolia, an important medicinal plant, is determined by the two main secondary metabolites of the root, purpurin and mollugin.
Yanlin Wang, Yanlin Wang, Yanlin Wang, Huanchu Liu, Huanchu Liu, Shuai Yu, Shuai Yu, Yue Zhang, Yue Zhang, Yue Zhang, Yanqing Huang, Yanqing Huang, Yanqing Huang, Xingyuan He, Xingyuan He, Xingyuan He, Xingyuan He, Wei Chen, Wei Chen, Wei Chen, Wei Chen   +20 more
doaj   +2 more sources

Dynamic analysis of growth characteristics, secondary metabolites accumulation, and an in-depth understanding of anthraquinones biosynthesis in Rubia cordifolia Linn. [PDF]

Frontiers in Plant Science
Rubia cordifolia is a well-known plant used in oriental medicine plant, and is also serves as the primary traditional source of plant red dyestuffs. With the current depletion of natural resources of R.
Conglong Lian, Conglong Lian, Conglong Lian, Xiuyu Liu, Xiuyu Liu, Kaihua Guo, Kaihua Guo, Hao Yang, Hao Yang, Jingfan Yang, Jingfan Yang, Jinxu Lan, Jinxu Lan, Suiqing Chen, Suiqing Chen, Suiqing Chen, Suiqing Chen   +16 more
doaj   +2 more sources