Purpurin suppresses Candida albicans biofilm formation and hyphal development.
PLoS ONE, 2012 A striking and clinically relevant virulence trait of the human fungal pathogen Candida albicans is its ability to grow and switch reversibly among different morphological forms. Inhibition of yeast-to-hypha transition in C.
Paul Wai-Kei Tsang +2 more
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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins [PDF]
Scientific ReportsSalmonella Typhimurium (S. Typhimurium, ST) is a food-borne pathogen that can be transmitted from animals to humans and causes symptoms such as diarrhea, fever, and vomiting.
Zhenxu Shi +7 more
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Advances in Purpurin 18 Research: On Cancer Therapy [PDF]
Applied Sciences, 2021 How to make cancer treatment more efficient and enhance the patient’s outcome? By multimodal therapy, theranostics, or personalized medicine? These are questions asked by scientists and doctors worldwide.
Vladimíra Pavlíčková +3 more
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Activity of Hydrophilic, Biocompatible, Fluorescent, Organic Nanoparticles Functionalized with Purpurin-18 in Photodynamic Therapy for Colorectal Cancer [PDF]
NanomaterialsPhotodynamic therapy (PDT) is a clinically approved, non-invasive therapy currently used for several solid tumors, triggering cell death through the generation of reactive oxygen species (ROS).
Rayan Chkair +7 more
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Structural and functional insights into the selective inhibition of mutant tau aggregation by purpurin and oleocanthal in frontotemporal dementia. [PDF]
Protein SciAbstract Tau aggregation driven by microtubule‐associated protein tau (MAPT) mutations is central to frontotemporal dementia pathology, yet no disease‐modifying therapies effectively target mutant tau. Here, we identify purpurin (PUR) and oleocanthal (OLC) as selective inhibitors of mutant tau aggregation using peptide models spanning the R2R3 ...
Goud AC +5 more
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Multianalytical Study of Amuletic and Talismanic Islamic-African Paper Manuscripts in the Slovene Ethnographic Museum. [PDF]
ChempluschemThe image illustrates a multi‐technique analysis of Islamic‐African manuscripts from the nineteenth to twentieth centuries. It highlights methods like microscopy, hyperspectral imaging, FTIR, LIF, Raman, LIBS, and furnish analysis used to study paper fibers, inks, and dyes—revealing a blend of local and trade materials and a rich fusion of Qur’anic and
Elnaggar A +12 more
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HPLC, UV-Vis and NMR spectroscopic and DFT characterization of purpurin isolated from Rubia tinctorum L. [PDF]
Hemijska Industrija, 2013 Purpurin (1,2,4-trihidroxyanthraquinone), a naurally occuring anthraquinone pigment present in the root of Rubia tinctorum (Mull. Arg.) Zahlbr. was isolated from the plant, purified and characterized by HPLC chromatography, UV-Vis and NMR spectroscopy.
Marković Zoran S. +3 more
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Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms. [PDF]
PLoS ONE, 2013 Candida dubliniensis is an important human fungal pathogen that causes oral infections in patients with AIDS and diabetes mellitus. However, C. Dubliniensis has been frequently reported in bloodstream infections in clinical settings.
Paul Wai-Kei Tsang +3 more
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Some anticancer agents as effective glutathione S-transferase (GST) inhibitors
Open Chemistry, 2023 The objective of this research was to investigate the impact of anthraquinone (AQ) compounds on the activity of the enzyme glutathione S-transferase (GST).
Gökçe Başak
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Antibacterial activity of Rubia tinctorum extracts. [PDF]
Records of Pharmaceutical & Biomedical Sciences, 2022 Rubia tinctorum a root belonging to family Rubiaceae was evaluated for the antibacterial activity against a number of bacteria. We determine antibacterial activity of Alizarin, Purpurin, methanol and chloroform extracts of Rubia tinctorum roots against ...
Aya El Tanahy
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