A purpurin-based metalloimmunostimulant amplifies ROS and modulates STING/TNF-α axis to potentiate melanoma immunotherapy [PDF]
Materials Today BioThe low infiltration of pro-inflammatory immune cells and the sustained activation of multiple immunosuppressive signaling pathways in melanoma significantly limit the efficacy of clinical immunotherapy. Therefore, developing an effective immunostimulant
Xiaoxin Yang +7 more
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Anthraquinones Inhibit Insulin Amyloidosis in Crowded Environments [PDF]
MoleculesNatural anthraquinones possess a wide range of biological activities, including antibacterial, antiviral, antitumor, and antioxidant effects. However, studies on their ability to inhibit amyloid protein aggregation remain relatively limited.
Jiaxing Zhang +5 more
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Purpurin suppresses Candida albicans biofilm formation and hyphal development.
PLoS ONE, 2012 A striking and clinically relevant virulence trait of the human fungal pathogen Candida albicans is its ability to grow and switch reversibly among different morphological forms. Inhibition of yeast-to-hypha transition in C.
Paul Wai-Kei Tsang +2 more
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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins [PDF]
Scientific ReportsSalmonella Typhimurium (S. Typhimurium, ST) is a food-borne pathogen that can be transmitted from animals to humans and causes symptoms such as diarrhea, fever, and vomiting.
Zhenxu Shi +7 more
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Activity of Hydrophilic, Biocompatible, Fluorescent, Organic Nanoparticles Functionalized with Purpurin-18 in Photodynamic Therapy for Colorectal Cancer [PDF]
NanomaterialsPhotodynamic therapy (PDT) is a clinically approved, non-invasive therapy currently used for several solid tumors, triggering cell death through the generation of reactive oxygen species (ROS).
Rayan Chkair +7 more
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HPLC, UV-Vis and NMR spectroscopic and DFT characterization of purpurin isolated from Rubia tinctorum L. [PDF]
Hemijska Industrija, 2013 Purpurin (1,2,4-trihidroxyanthraquinone), a naurally occuring anthraquinone pigment present in the root of Rubia tinctorum (Mull. Arg.) Zahlbr. was isolated from the plant, purified and characterized by HPLC chromatography, UV-Vis and NMR spectroscopy.
Marković Zoran S. +3 more
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Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms. [PDF]
PLoS ONE, 2013 Candida dubliniensis is an important human fungal pathogen that causes oral infections in patients with AIDS and diabetes mellitus. However, C. Dubliniensis has been frequently reported in bloodstream infections in clinical settings.
Paul Wai-Kei Tsang +3 more
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Some anticancer agents as effective glutathione S-transferase (GST) inhibitors
Open Chemistry, 2023 The objective of this research was to investigate the impact of anthraquinone (AQ) compounds on the activity of the enzyme glutathione S-transferase (GST).
Gökçe Başak
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Antibacterial activity of Rubia tinctorum extracts. [PDF]
Records of Pharmaceutical & Biomedical Sciences, 2022 Rubia tinctorum a root belonging to family Rubiaceae was evaluated for the antibacterial activity against a number of bacteria. We determine antibacterial activity of Alizarin, Purpurin, methanol and chloroform extracts of Rubia tinctorum roots against ...
Aya El Tanahy
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Zur Kenntniss des Purpurins. Verwandlung des Purpurins in Chinizarin [PDF]
Berichte der deutschen chemischen Gesellschaft, 1877 n ...
Schunck, E., Roemer, H.
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