Results 141 to 150 of about 21,294 (218)

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

MPRIP-ALK, a Novel ALK Rearrangement That Responds to ALK Inhibition in NSCLC [PDF]

Journal of Thoracic Oncology, 2019
Wenfeng Fang, Jiadi Gan, Shaodong Hong, Feng Lu, Li Zhang   +4 more
openaire   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy, Raymond Barnhill, Boris C. Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony Gill, Jennelle C. Hodge, Joseph D Khoury, Katia Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Liang Zhiyong, Holger Moch, Rajendra Singh, Harshima Wijesinghe, Ian Cree, Dilani Lokuhetty   +29 more
wiley   +1 more source

Pathologic assessment of resected stage III non‐small cell lung cancer after neoadjuvant chemotherapy: identification of additional prognostic factors

Histopathology, Volume 88, Issue 3, Page 710-728, February 2026.
Multiple pathological variables are associated with prognosis in resected NSCLC at stage III undergoing neoadjuvant treatment, namely vascular, perineural and pleural infiltration, proliferation index, pathological response, fibrosis and presence of lymphocytes in the tumour bed.
Francesca Lunardi, Alessandra Ferro, Luca Vedovelli, Federica Pezzuto, Sofia‐Eleni Tzorakoleftheraki, Asuman Kilitci, Yuliia Kuzyk, Simone Zanella, Marco Schiavon, Federico Rea, Giulia Pasello, Fiorella Calabrese   +11 more
wiley   +1 more source

Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged nonsmall cell lung cancer and beyond

Drug Design, Development and Therapy, 2011
Sai-Hong Ignatius OuChao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CAAbstract: Epidermal growth factor receptor (EGFR) tyrosine inhibitors were first approved for the treatment of non-small cell lung ...
Ou SH
doaj  

An unresectable and metastatic intrahepatic cholangiocarcinoma with EML4-ALK rearrangement achieving partial response after first-line treatment with ensartinib: a case report. [PDF]

Front Oncol, 2023
Huang S, Li D, Huang Y, Lu G, Tian Y, Zhong X, Zheng Y, Huang M, Huang F.   +8 more
europepmc   +1 more source

Clinicopathological and Prognostic Significance of EML4-ALK Rearrangement in Patients with Surgically Resected Lung Adenocarcinoma: A Propensity Score Matching Study

Cancer Management and Research, 2020
Jinghan Shi, 1,* Weiqing Gu, 2,* Yanfeng Zhao, 1 Junjie Zhu, 1 Gening Jiang, 1 Minwei Bao, 1 Jingyun Shi 3 1Department of Thoracic Surgery, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, People’s Republic of China ...
Shi J, Gu W, Zhao Y, Zhu J, Jiang G, Bao M, Shi J   +6 more
doaj  

Arterial and Venous Thromboembolism in ALK-Rearrangement-Positive Non-small Cell Lung Cancer: A Population-Based Cohort Study. [PDF]

Oncologist, 2023
Icht O, Leader A, Batat E, Yosef L, Shochat T, Goldstein DA, Dudnik E, Spectre G, Raanani P, Hammerman A, Zer A.   +10 more
europepmc   +1 more source

Radiomic features and tumor immune microenvironment associated with anaplastic lymphoma kinase-rearranged lung adenocarcinoma and their prognostic value

Frontiers in Genetics
PurposeTo identify radiomic features from preoperative computed tomography (CT) images and characteristics of the tumor immune microenvironment (TIME) associated with anaplastic lymphoma kinase (ALK) rearrangement in patients with lung adenocarcinomas ...
Ying Han, Wenya Feng, Wenya Feng, Huaxin Li, Hua Wang, Hua Wang, Zhaoxiang Ye   +6 more
doaj   +1 more source

ALK Gene Rearrangement [PDF]

, 2020
openaire   +1 more source